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dc.contributor.authorScorza, Fulvio A. [UNIFESP]
dc.contributor.authorCysneiros, Roberta M.
dc.contributor.authorTerra, Vera C.
dc.contributor.authorScorza, Carla A. [UNIFESP]
dc.contributor.authorCavalheiro, Esper A. [UNIFESP]
dc.contributor.authorRibeiro, Miriam O.
dc.contributor.authorGattaz, Wagner F.
dc.identifier.citationProstaglandins Leukotrienes and Essential Fatty Acids. Oxford: Elsevier B.V., v. 81, n. 4, p. 241-245, 2009.
dc.description.abstractPeople with schizophrenia show a two- to three-fold increased risk to die prematurely. Mortality is accounted for by a combination of factors (patients' life style, suicide, premature cardiovascular disease, metabolic syndromes and, not so often mentioned, sudden death). the cause of sudden death in schizophrenia is unknown, but cardiac arrhythmia plays a potential role. Patients with schizophrenia are at high risk for cardiovascular disease, and some antipsychotics may be associated with cardiovascular adverse events (e.g., electrocardiograph QT interval prolongation), suggesting that this could lead to sudden cardiac death. Animal and clinical studies have shown that omega-3 fatty acids could be useful in the prevention and treatment of schizophrenia. As omega-3 fatty acids have been considered a cardioprotector agent, reducing cardiac arrhythmias and hence sudden cardiac deaths and given their relative safety and general health benefits, our update article summarizes the knowledge by g the possible positive effects of omega-3 supplementation and fish consumption against sudden cardiac death in patients with schizophrenia. However, fish species should be selected with caution due to contamination with toxic methylmercury. (C) 2009 Elsevier B.V. All rights reserved.en
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.publisherElsevier B.V.
dc.relation.ispartofProstaglandins Leukotrienes and Essential Fatty Acids
dc.rightsAcesso restrito
dc.subjectSudden cardiac deathen
dc.titleOmega-3 consumption and sudden cardiac death in schizophreniaen
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.contributor.institutionUniv Presbiteriana Mackenzie
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.description.affiliationUniversidade Federal de São Paulo, Disciplina Neurol Expt, Escola Paulista Med, BR-04023900 São Paulo, Brazil
dc.description.affiliationUniv Presbiteriana Mackenzie, Programa Posgrad Disturbios Desenvolvimento, Ctr Ciencias Biol & Saude, São Paulo, Brazil
dc.description.affiliationUniv São Paulo, Dept Neurociencias & Ciencias Comportamento, Fac Med Ribeirao Preto, São Paulo, Brazil
dc.description.affiliationUniv São Paulo, Fac Med, Dept & Inst Psiquiatria, Lab Neurociencia,LIM 27, São Paulo, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Disciplina Neurol Expt, Escola Paulista Med, BR-04023900 São Paulo, Brazil
dc.description.sourceWeb of Science
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