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dc.contributor.authorSantos Silva, Amanda Goncalves dos [UNIFESP]
dc.contributor.authorSarkar, Rahul
dc.contributor.authorHarizanova, Jana
dc.contributor.authorGuffei, Amanda
dc.contributor.authorMowat, Michael
dc.contributor.authorGarini, Yuval
dc.contributor.authorMai, Sabine
dc.identifier.citationJournal of Cellular Biochemistry. Hoboken: Wiley-Blackwell, v. 104, n. 6, p. 2040-2058, 2008.
dc.description.abstractAs the spindle fiber attachment region of the chromosome, the centromere has been investigated in a variety of contexts. Here, we will review current knowledge about this unique chromosomal region and its relevance for proper cell division, speciation, and disease. Understanding the three-dimensional organization of centromeres in normal and turner cells is just beginning to emerge. Multidisciplinary research will allow for new insights into its normal and aberrant nuclear organization and may allow for new therapeutic interventions that target events linked to centromere function and cell division.en
dc.relation.ispartofJournal of Cellular Biochemistry
dc.rightsAcesso restrito
dc.subjectcell divisionen
dc.subject3D nucleusen
dc.titleCentromeres in cell division, evolution, nuclear organization and diseaseen
dc.contributor.institutionUniv Manitoba
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.contributor.institutionSunnybrook Hlth Sci Ctr
dc.contributor.institutionBar Ilan Univ
dc.description.affiliationUniv Manitoba, CancerCare Manitoba, Manitoba Inst Cell Biol, Winnipeg, MB R3E 0V9, Canada
dc.description.affiliationUniversidade Federal de São Paulo, Dept Microbiol Imunol & Parasitol, Disciplina Imunol, São Paulo, Brazil
dc.description.affiliationSunnybrook Hlth Sci Ctr, Dept Imaging Res, Toronto, ON M4N 3M5, Canada
dc.description.affiliationBar Ilan Univ, Dept Phys, Ramat Gan, Israel
dc.description.affiliationBar Ilan Univ, Nanotechnol Inst, Ramat Gan, Israel
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Dept Microbiol Imunol & Parasitol, Disciplina Imunol, São Paulo, Brazil
dc.description.sourceWeb of Science
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