Please use this identifier to cite or link to this item: https://repositorio.unifesp.br/handle/11600/30814
Title: Prospective randomized comparison of oxybutynin, functional electrostimulation, and pelvic floor training for treatment of detrusor overactivity in women
Authors: Arruda, Raquel M. [UNIFESP]
Castro, Rodrigo A. [UNIFESP]
Sousa, Gabriela C. [UNIFESP]
Sartori, Marair G. F. [UNIFESP]
Baracat, Edmund C. [UNIFESP]
Girao, Manoel J. B. C. [UNIFESP]
Universidade Federal de São Paulo (UNIFESP)
Keywords: overactive bladder
detrusor overactivity
urinary incontinence
pelvic floor training
electrical stimulation
Issue Date: 1-Aug-2008
Publisher: Springer
Citation: International Urogynecology Journal. London: Springer London Ltd, v. 19, n. 8, p. 1055-1061, 2008.
Abstract: The purpose of this study is to compare the effectiveness of oxybutynin, functional electrostimulation (FES), and pelvic floor training (PFT) for treatment of women with detrusor overactivity. Sixty-four subjects were randomized to oxybutynin (n = 22), FES (n = 21), or PFT (n = 21). Women were evaluated before and after completion of 12 weeks of treatment by subjective response, voiding diary, and urodynamic test. There was subjective symptomatic improvement in 77% of the women treated with oxybutynin, 52% with FES, and 76% with PFT. Urgency resolved in 64% of women treated with oxybutynin, 52% with FES, and in 57% with PFT. Urodynamic evaluation was normal in 36% treated with oxybutynin, 57% with FES, and 52% with PFT. Maximum detrusor involuntary contraction pressure decreased in all groups (p < 0.05). All treatments were equally effective. Subjective reduction of urge-incontinence episodes was associated with symptomatic improvement.
URI: http://repositorio.unifesp.br/handle/11600/30814
ISSN: 0937-3462
Other Identifiers: http://dx.doi.org/10.1007/s00192-008-0586-y
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