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Title: Hippocampal sclerosis and status epilepticus - cause or consequence? A MRI study
Authors: Kuster, Gustavo Wruck [UNIFESP]
Braga-Neto, Pedro [UNIFESP]
Santos-Neto, Denizart [UNIFESP]
Garcia Santana, Maria Teresa [UNIFESP]
Martins Maia, Antonio Carlos
Barsottini, Orlando Graziani Povoas [UNIFESP]
Fleury Inst
Universidade Federal de São Paulo (UNIFESP)
Keywords: status epilepticus
magnetic resonance imaging (MRI)
diffusion-weighted images
reversible MRI abnormalities
hippocampal sclerosis
Issue Date: 1-Dec-2007
Publisher: Assoc Arquivos Neuro- Psiquiatria
Citation: Arquivos de Neuro-psiquiatria. São Paulo, SP: Assoc Arquivos Neuro- Psiquiatria, v. 65, n. 4B, p. 1101-1104, 2007.
Abstract: Background: Transient imaging abnormalities, including changes on diffusion-weighted imaging (DWI), maybe seen in status epilepticus. These abnormalities can be followed by hippocampal sclerosis. Case report: We report a 15-year-old lady with focal non convulsive status epilepticus (NCSE) and focal slowing on EEG. DWI exhibited abnormal hyperintense signals in bilateral temporal and insular cortices. After 3 weeks, MRI performed a localizated hippocampal atrophy. Conclusion: the MRI findings indicated vasogenic and cytotoxic edema during seizure activity and subsequent loss of brain parenchyma.
ISSN: 0004-282X
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