Please use this identifier to cite or link to this item: http://repositorio.unifesp.br/handle/11600/30118
Title: Brazilian normal static bone histomorphometry: effects of age, sex, and race
Authors: Dos Reis, Luciene M.
Batalha, Joao R.
Munoz, Daniel R.
Borelli, Aurelio
Correa, Pedro H. S.
Carvalho, Aluizio B.
Jorgetti, Vanda
Universidade de São Paulo (USP)
Universidade Federal de São Paulo (UNIFESP)
Keywords: bone histomorphometry
age-related bone loss
race and sex differences
normal iliac bone
Issue Date: 1-Nov-2007
Publisher: Springer
Citation: Journal of Bone and Mineral Metabolism. Tokyo: Springer Tokyo, v. 25, n. 6, p. 400-406, 2007.
Abstract: Bone histomorphometry values for normal individuals within different populations have been well established. We studied iliac crest bone samples from 125 healthy Brazilian subjects. the effect of sex, race, and age variables on histomorphometric parameters was evaluated. Bone volume showed a trend to decrease with age in both sexes, being significantly higher in black females and Caucasian males. Interactions among sex, race, and age had no effect on trabecular thickness (Tb.Th) and trabecular separation (Tb.Sp). However, age had a significant effect on Tb.Th and Tb.Sp, and sex had an impact on Tb.Sp. Trabecular number (Tb.N) was higher in black females than in males and was higher in Asian males than in females. Among females, Tb.N was lower in Asians than in other races and was higher in blacks than in Caucasians and or in those of mulattos. in addition, Tb.N was higher in males under 10 than in males over 50 years old, was higher in females under 10 than in females in any other age bracket, and was lower in females in the 41-50 age bracket than in younger females. Osteoid volume and osteoid surface were significantly higher in males than in females, and a significant age-related difference in osteoid thickness was observed. No significant sex-related or race-related differences were found in terms of resorption, although eroded surface decreased with age. in conclusion, sex, race, and age, as well as interactions among these three variables, were found to affect some static histomorphometric indexes in healthy Brazilian subjects.
URI: http://repositorio.unifesp.br/handle/11600/30118
ISSN: 0914-8779
Other Identifiers: http://dx.doi.org/10.1007/s00774-007-0778-4
Appears in Collections:Em verificação - Geral

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