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Title: Clinical features and outcomes of 134 Brazilians with acute promyelocytic leukemia who received ATRA and anthracyclines
Authors: Jacomo, Rafael Henriques
Morais Melo, Raul Antonio
Souto, Fernanda Ribeiro
Mattos, Ederson Roberto de
Oliveira, Claudia Teresa de
Fagundes, Evandro M.
Silva Bittencourt, Henrique Neves da
Bittencourt, Rosane Isabel
Bortolheiro, Teresa Cristina
Paton, Eduardo J. A.
Bendlin, Rodrigo
Ismael, Sebastiao
Chauffaille, Maria de Lourdes Lopes Ferrari [UNIFESP]
Silva, Dirceu
Pagnano, Katia Borgia B.
Ribeiro, Raul
Rego, Eduardo M.
Med Sch Riberao Preto
Hosp Amaral Carvalho
Universidade Federal de Minas Gerais (UFMG)
Santa Casa São Paulo
Fundacao Pio XII Barretos
Clin Hematol Riberao Preto
Universidade Federal de São Paulo (UNIFESP)
Universidade Estadual de Campinas (UNICAMP)
St Jude Childrens Hosp
Keywords: acute promyelocytic leukemia
developing countries
Issue Date: 1-Oct-2007
Publisher: Ferrata Storti Foundation
Citation: Haematologica-the Hematology Journal. Pavia: Ferrata Storti Foundation, v. 92, n. 10, p. 1431-1432, 2007.
Abstract: We report an increased incidence of high relapse risk features in 157 APL Brazilian patients. Out of 134 patients treated with ATRA and anthracyclines, only 91 (67.9%) achieved remission because 43 (32%) died during induction. the death rate during consolidation was 10.5%. Bleeding complications were the most frequent cause of failure (21.6%).
ISSN: 0390-6078
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