Please use this identifier to cite or link to this item:
|Title:||Effects of different types of physical exercise on the staining of parvalbumin-positive neurons in the hippocampal formation of rats with epilepsy|
|Authors:||Arida, Ricardo Mario|
Scorza, Carla Alessandra
Scorza, Fulvio Alexandre
Silva, Sergio Gomes da
Naffah-Mazzacoratti, Maria da Graca
Cavalheiro, Esper Abrao
Universidade Federal de São Paulo (UNIFESP)
Univ Mogi das Cruzes
|Citation:||Progress in Neuro-psychopharmacology & Biological Psychiatry. Oxford: Pergamon-Elsevier B.V., v. 31, n. 4, p. 814-822, 2007.|
|Abstract:||Effects of exercise in animals with epilepsy have been demonstrated. To investigate whether the type of physical activity, voluntary or forced, would promote different morphological changes in hippocampal formation we performed an immunocytochemical study using the parvalbumin (PV) distribution as a marker. Control rats and rats with epilepsy were submitted to a voluntary (wheel running) and forced (treadmill) exercise for 10 days (acute physical exercise) or 45 days (chronic physical exercise). It was observed in normal rats a higher number of PV-positive cells in the hilus of dentate gyrus (DG) in the voluntary and forced exercise groups (acute and chronic physical exercise), when compared to the control group. in animals with epilepsy the number of PV-positive cells and staining intensity of PV-fibers in the hilus was significantly higher only in the acute physical exercise (voluntary and forced). These findings demonstrate that acute physical exercise, both voluntary and forced results in increased number of PV-positive cells and staining intensity of PV-fibers in the hilus of rats with epilepsy and the occurrence of these changes takes place only in the early phase of epilepsy. (c) 2007 Published by Elsevier Inc.|
|Appears in Collections:||Em verificação - Geral|
Files in This Item:
There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.