Please use this identifier to cite or link to this item: https://repositorio.unifesp.br/handle/11600/29393
Title: Treatment of moderate obstructive sleep apnea syndrome with acupuncture: A randomised, placebo-controlled pilot trial
Authors: Freire, Anaflavia de Oliveira [UNIFESP]
Sugai, Gisele C. M.
Chrispin, Fernanda Silveira
Togeiro, Sonia Maria
Yamamura, Ysao
Mello, Luiz Eugenio
Tufik, Sergio [UNIFESP]
Universidade Federal de São Paulo (UNIFESP)
Keywords: acupuncture
obstructive sleep apnea syndrome
polysomnography
quality of life
excessive daytime sleepiness
Issue Date: 1-Jan-2007
Publisher: Elsevier B.V.
Citation: Sleep Medicine. Amsterdam: Elsevier B.V., v. 8, n. 1, p. 43-50, 2007.
Abstract: Background and purpose: To investigate the efficacy of acupuncture in the treatment of moderate obstructive sleep apnea syndrome (OSAS), assessed by polysomnography (PSG) and questionnaires of functional quality of life (SF-36) and excessive daytime sleepiness (Epworth).Patients and methods: We performed a randomised, placebo-controlled, single-blinded study, with blinded evaluation on 36 patients presenting an apnea/hypopnea index (AHI) of 15-30/h, assessed by PSG. the study took place at the Public Hospital of the Universidade Federal de S (a) over tildeo Paulo, Brazil, in the Division of Sleep Disorders of the Department of Psychobiology, between January, 2002 and August, 2004. Patients were randomly assigned to three groups: the acupuncture group (n = 12); the sham group, submitted to needle insertion in non-acupoints (n = 12); and the control group, receiving no treatment (n = 12). Patients received acupuncture or sham acupuncture once a week for 10 weeks.Results: Twenty-six patients completed the study. the AHI (P = 0.005), the apnea index (AI) (P = 0.008) and the number of respiratory events (P = 0.005) decreased significantly in the acupuncture group but not in the sham group. On the other hand, the control group displayed significant deterioration in some of the polysomnographic parameters, with a significant increase in the n umber of respiratory events (P = 0.025). Acupuncture treatment significantly improved (before vs. after treatment) several dimensions of the SF-36 and Epworth questionnaires. There was no significant association between changes in the body mass index (BMI) and AHI.Conclusions: Acupuncture is more effective than sharn acupuncture in ameliorating the respiratory events of patients presenting with moderate OSAS. (c) 2006 Elsevier B.V. All rights reserved.
URI: http://repositorio.unifesp.br/handle/11600/29393
ISSN: 1389-9457
Other Identifiers: http://dx.doi.org/10.1016/j.sleep.2006.04.009
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