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Title: Prevalence of vancomycin-resistant Enterococcus fecal colonization among kidney transplant patients
Authors: Freitas, Maria Cecília de Santos [UNIFESP]
Pacheco-Silva, Alvaro [UNIFESP]
Barbosa, Dulce Aparecida [UNIFESP]
Silbert, Suzane [UNIFESP]
Sader, Helio Silva [UNIFESP]
Sesso, Ricardo de Castro Cintra [UNIFESP]
Camargo, Luis Fernando Aranha [UNIFESP]
Universidade Federal de São Paulo (UNIFESP)
Issue Date: 22-Aug-2006
Publisher: Biomed Central Ltd
Citation: Bmc Infectious Diseases. London: Biomed Central Ltd, v. 6, 7 p., 2006.
Abstract: Background: End stage renal disease patients are at risk of Vancomycin-Resistant Enterococcus (VRE) infections. the first reports of VRE isolation were from hemodialysis patients. However, to date, VRE fecal colonization rates as well as associated risk factors in kidney transplant patients have not yet been established in prospective studies.Methods: We collected one or two stool samples from 280 kidney transplant patients and analysed the prevalence of VRE and its associated risk factors. Patients were evaluated according to the post-transplant period: group 1, less than 30 days after transplantation ( 102 patients), group 2, one to 6 months after transplantation ( 73 patients) and group 3, more than 6 months after transplantation ( 105 patients).Results: the overall prevalence rate of fecal VRE colonization was 13.6% (38/280), respectively 13.7% for Group 1, 15.1% for group 2 and 12.4% for group 3. E. faecium and E. faecalis comprised 50% of all VRE isolates. No immunologic variables were clearly correlated with VRE colonization and no infections related to VRE colonization were reported.Conclusion: Fecal VRE colonization rates in kidney transplant patients were as high as those reported for other high-risk groups, such as critical care and hemodialysis patients. This high rate of VRE colonization observed in kidney transplant recipients may have clinical relevance in infectious complications.
ISSN: 1471-2334
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