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Title: Cavectomy for the treatment of Wilms tumor with vascular extension
Authors: Ribeiro, R. C.
Schettini, Sergio T.omaz [UNIFESP]
Abib, Simone de Campos Vieira [UNIFESP]
Fonseca, José Honório de Almeida Palma da [UNIFESP]
Cypriano, Monica [UNIFESP]
Silva, Nasjla Saba da [UNIFESP]
Universidade Federal de São Paulo (UNIFESP)
Keywords: Wilms tumor
vena cava
venous thrombosis
kidney neoplasms
Issue Date: 1-Jul-2006
Publisher: Lippincott Williams & Wilkins
Citation: Journal of Urology. Philadelphia: Lippincott Williams & Wilkins, v. 176, n. 1, p. 279-283, 2006.
Abstract: Purpose: Vascular extension to the vena cava occurs in 4% of Wilms tumor cases and can reach the right atrium in up to 1%. When this happens the thrombus is usually not adherent to the vessel wall, and there is blood flow around it. Preoperative chemotherapy can cause thrombus regression and even resolution. If the thrombus persists after chemotherapy, surgery will be a challenge. On the other hand, if the thrombus invades the vessel wall, its removal may not be feasible. in this situation cavectomy is a good surgical strategy because it provides complete resection. the prerequisite for cavectomy is the absence of blood flow in the vena cava on preoperative Doppler ultrasonography. We report 3 cases of Wilms tumor with vena caval invasion in which cavectomy was performed, and discuss the principles, indications and operative technique.Materials and Methods: A total of 171 patients with Wilms tumor were treated at our institution between 1984 and 2004. of these patients 6 with intravascular extension of thrombus within the right atrium were treated with extracorporeal. circulation, cardiac arrest and profound hypothermia, and 3 were treated with cavectomy.Results: There were no instances of surgical complications or postoperative renal failure in our patients who underwent cavectomy. All remain well and free of disease.Conclusions: Cavectomy is a safe procedure for treating pediatric patients with Wilms tumor when there is extension and invasion of the vena cava wall without blood flow.
ISSN: 0022-5347
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