Please use this identifier to cite or link to this item: https://repositorio.unifesp.br/handle/11600/28687
Title: A cohort study to assess the impact of depression on patients with kidney disease
Authors: Zimmermann, Paulo Roberto
Camey, Suzi Alves
Mari, Jair de Jesus [UNIFESP]
Pontificia Univ Catolica Rio Grande do Sul
Univ Fed Rio Grande do Sul
Universidade Federal de São Paulo (UNIFESP)
Keywords: renal replacement therapy
cohort studies
depressive disorders
quality of life
mortality
Issue Date: 1-Jan-2006
Publisher: Baywood Publ Co Inc
Citation: International Journal of Psychiatry in Medicine. Amityville: Baywood Publ Co Inc, v. 36, n. 4, p. 457-468, 2006.
Abstract: Aims: This study assessed the impact of depression on mortality and quality of life of patients with kidney disease. Material: This study was conducted at Hospital Sao Lucas of Pontificia Universidade Catolica of Rio Grande do Sul, Porto Alegre, Brazil, with a cohort of 125 patients seen from 1996 to 2004. (mean follow-up = 77.6 months). Patients undergoing renal replacement therapy were asked to fill in the Beck Depression Inventory (BDI). At the completion of follow-up, 72 patients were alive, and 56 answered the BDI and the Medical Outcome Study Short Form General Health Survey (SF-36) to assess quality of life, Main outcome measures were mortality and quality of life. Results: Initial analysis showed that mortality was associated with age, treatment modality-continuous ambulatory peritoneal dialysis (CAPD) or hemodialysis (hd)-and depression. When controlling for age, gender, depression, and treatment modality in a multiple regression analysis, transplantation (tx), gender and age was associated with lower mortality. However, levels of depression at the end of follow-up were strongly associated with quality of life. Conclusions: Depression was not associated with mortality of Patients with kidney disease when controlling for gender, age, and treatment: modality. Transplantation was the main factor associated with lower mortality. Depression was, however, a strong predictor of quality of life. Number of depressive symptoms was directly associated with lower quality of life in most of the items of the SF-36.
URI: http://repositorio.unifesp.br/handle/11600/28687
ISSN: 0091-2174
Other Identifiers: http://ijp.sagepub.com/content/36/4/457.abstract
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