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Title: Severe ankylosing spondylitis and diffuse systemic sclerosis: case report of a genetic trap
Authors: Kayser, Cristiane [UNIFESP]
Alvarenga, MCV [UNIFESP]
Neves, A. S. [UNIFESP]
Gerbase-Lima, Maria [UNIFESP]
Andrade, Luiz Eduardo Coelho [UNIFESP]
Universidade Federal de São Paulo (UNIFESP)
Issue Date: 1-Apr-2005
Publisher: Taylor & Francis As
Citation: Scandinavian Journal of Rheumatology. Oslo: Taylor & Francis As, v. 34, n. 2, p. 145-147, 2005.
Abstract: A rare association of ankylosing spondylitis ( AS) and systemic sclerosis (SSc) is reported in a Brazilian Mestizo patient presenting a human leucocyte antigen (HLA) genotype that included HLA SSc-susceptibility genes previously reported in different ethnic groups and HLA-B27 associated with AS. the underlying genetic background supporting the full expression of both SSc- and AS-susceptibility alleles and the pertinent literature are discussed.
ISSN: 0300-9742
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