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https://repositorio.unifesp.br/handle/11600/28182| Title: | Chronic myeloid leukemia following kidney transplantation |
| Authors: | Pelloso, LAF Campos, MGV de Nascimento, M. Silva, MRR Pestana, JOM Chauffaille, MDLF Universidade Federal de São Paulo (UNIFESP) |
| Keywords: | chronic myeloid leukemia chemically induced leukemia kidney transplantation immunossupressive drugs immunossupression azathioprine |
| Issue Date: | 1-Mar-2005 |
| Publisher: | Elsevier B.V. |
| Citation: | Leukemia Research. Oxford: Pergamon-Elsevier B.V., v. 29, n. 3, p. 353-355, 2005. |
| Abstract: | Immunosuppressed renal recipients are at an increased risk of developing cancer. Leukemias are less frequent than other hematopoietic tumours and development of CML after immunosuppression is rare. We describe a 37-year-old male who presented with left-shifted leukocytosis, hypercellular bone marrow 32 months after the kidney transplant. G-banding karyotype revealed 46,XY,t(9;22)(q34;q11) and the diagnosis of chronic myeloid leukemia was made. This is the 13th case of CML after kidney transplant reported. Whether this CML appeared as a random phenomenon or chemically induced is a matter of debate. Some individuals might have an increased susceptibility to the effects of azathioprine. (C) 2004 Elsevier B.V. All rights reserved. |
| URI: | http://repositorio.unifesp.br/handle/11600/28182 |
| ISSN: | 0145-2126 |
| Other Identifiers: | http://dx.doi.org/10.1016/j.leukres.2004.07.008 |
| Appears in Collections: | Artigo Artigo |
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