Please use this identifier to cite or link to this item: http://repositorio.unifesp.br/handle/11600/27712
Title: Heavier-than-air flying machines are impossible
Authors: Oliveira, Laerte [UNIFESP]
Hulsen, T.
Hulsik, D. L.
Paiva, Antonio Cechelli de Mattos [UNIFESP]
Vriend, Gerrit
KUN
Universidade Federal de São Paulo (UNIFESP)
Univ Utrecht
Keywords: GPCR
modelling
bovine rhodopsin
bacteriorhodopsin
superposition
alignment
Issue Date: 30-Apr-2004
Publisher: Elsevier B.V.
Citation: Febs Letters. Amsterdam: Elsevier B.V., v. 564, n. 3, p. 269-273, 2004.
Abstract: Many G protein-coupled receptor (GPCR) models have been built over the years. the release of the structure of bovine rhodopsin in August 2000 enabled us to analyze models built before that period to learn more about the models we build today. We conclude that the GPCR modelling field is riddled with 'common knowledge' similar to Lord Kelvin's remark in 1895 that heavier-than-air flying machines are impossible, and we summarize what we think are the (im)possibilities of modelling GPCRs using the coordinates of bovine rhodopsin as a template. Associated WWW pages: http://www.gpcr.org/ articles/2003_mod/. (C) 2004 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved.
URI: http://repositorio.unifesp.br/handle/11600/27712
ISSN: 0014-5793
Other Identifiers: http://dx.doi.org/10.1016/S0014-5793(04)00320-5
Appears in Collections:Em verificação - Geral

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