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Title: Heavier-than-air flying machines are impossible
Authors: Oliveira, Laerte [UNIFESP]
Hulsen, T.
Hulsik, D. L.
Paiva, Antonio Cechelli de Mattos [UNIFESP]
Vriend, Gerrit
Universidade Federal de São Paulo (UNIFESP)
Univ Utrecht
Keywords: GPCR
bovine rhodopsin
Issue Date: 30-Apr-2004
Publisher: Elsevier B.V.
Citation: Febs Letters. Amsterdam: Elsevier B.V., v. 564, n. 3, p. 269-273, 2004.
Abstract: Many G protein-coupled receptor (GPCR) models have been built over the years. the release of the structure of bovine rhodopsin in August 2000 enabled us to analyze models built before that period to learn more about the models we build today. We conclude that the GPCR modelling field is riddled with 'common knowledge' similar to Lord Kelvin's remark in 1895 that heavier-than-air flying machines are impossible, and we summarize what we think are the (im)possibilities of modelling GPCRs using the coordinates of bovine rhodopsin as a template. Associated WWW pages: articles/2003_mod/. (C) 2004 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved.
ISSN: 0014-5793
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Appears in Collections:Em verificação - Geral

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