Please use this identifier to cite or link to this item:
|Title:||Paradoxical sleep deprivation potentiates amphetamine-induced behavioural sensitization by increasing its conditioned component|
Andersen, M. L.
Araujo, N. P. de
Chinen, C. C.
Universidade Federal de São Paulo (UNIFESP)
|Keywords:||paradoxical sleep deprivation|
|Citation:||Brain Research. Amsterdam: Elsevier B.V., v. 1003, n. 1-2, p. 188-193, 2004.|
|Abstract:||The effects of paradoxical sleep deprivation (PSD-48 h) on the conditioned and unconditioned components of behavioural sensitization to amphetamine (two injections of 2.0 mg/kg, separated by 7 days) were studied using locomotion frequency of mice observed in an open-field as experimental parameter. Behavioural sensitization only occurred in PS deprived mice that were exposed to the open-field after the first amphetamine injection. the possible involvement of PSD in the development of a Pavlovian association between the stimulant effect of amphetamine and environmental as well as interoceptive drug cues is discussed. (C) 2004 Elsevier B.V. All rights reserved.|
|Appears in Collections:||Em verificação - Geral|
Files in This Item:
There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.