Please use this identifier to cite or link to this item: https://repositorio.unifesp.br/handle/11600/27614
Title: Frequency and characteristics of diarrhoeagenic Escherichia coli strains isolated from children with and without diarrhoea in Rio de Janeiro, Brazil
Authors: Regua-Mangia, A. H.
Gomes, TAT
Vieira, MAM
Andrade, JRC
Irino, K.
Teixeira, L. M.
Escola Nacl Saude Publica
Universidade Federal de São Paulo (UNIFESP)
Universidade do Estado do Rio de Janeiro (UERJ)
Inst Adolfo Lutz Registro
Universidade Federal do Rio de Janeiro (UFRJ)
Keywords: diarrhoeal disease
Escherichia coli
genotypic traits
phenotypic traits
clinical features
Issue Date: 1-Feb-2004
Publisher: W B Saunders Co Ltd
Citation: Journal of Infection. London: W B Saunders Co Ltd, v. 48, n. 2, p. 161-167, 2004.
Abstract: The frequency of diarrhoeagenic Escherichia coli (DEC) strains was investigated in 253 children up to 3 years old, with (patient group, PG, 199 children) and without (control group, CG, 54 children) diarrhoea, living in Rio de Janeiro, Brazil. DEC strains were detected in 70 (27.6%) children, including 54 (27.1%) with diarrhoea and 16 (29.6%) without diarrhoea. Enteroaggregative E. coli (EAEC) was the most frequent DEC category, accounting for 14.6% of the isolates in the PG and for 11.1% in the CG. E. coli strains carrying enteropathogenic E. coli (EPEC) virulence markers showed higher incidence in the CG (12.9%) than in the PG (8.0%). E. coli strains belonging to non-classical, EPEC groups that carried eae only or eae and bfpA, designated as attaching-effacing E. coli (AEEC) were the most frequent (79.1%). Simultaneous presence of multiple EPEC virulence factors (EAF/eae/bfpA) were only detected among strains isolated from the PG. Enterotoxigenic E. coli (ETEC) strains were isolated from 5.5% of the children in the CG and from 3.5% of those in the PG. Most of the ETEC isolates were LT-probe positive (70%) and none carried both LT-I and ST-I probe sequences. One enteroinvasive E. coli (EIEC) strain was recovered from a child with diarrhoea. No stx-probe positive E. coli strains were detected. Overall, DEC strains were not found to be significantly associated with diarrhoea (p > 0.05). However, the higher incidence of EAEC, the most frequent DEC category, among children with diarrhoea, suggests a potential role of EAEC as an important enteric pathogen in the community investigated. (C) 2003 the British Infection Society. Published by Elsevier B.V. All rights reserved.
URI: http://repositorio.unifesp.br/handle/11600/27614
ISSN: 0163-4453
Other Identifiers: http://dx.doi.org/10.1016/S0163-4453(03)00138-5
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