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Title: Mycobacteraemia among HIV-1-infected patients in São Paulo, Brazil: 1995 to 1998
Authors: Hadad, D. J.
Palaci, M.
Pignatari, ACC
Lewi, D. S.
Machado, MAS
Telles, MAS
Martins, M. C.
Ueki, SYM
Vasconcelos, G. M.
Palhares, MCA
Univ Fed Espirito Santo
Universidade Federal de São Paulo (UNIFESP)
Inst Adolfo Lutz Registro
Ctr Referencia & Treinamento AIDS
Issue Date: 1-Jan-2004
Publisher: Cambridge Univ Press
Citation: Epidemiology and Infection. New York: Cambridge Univ Press, v. 132, n. 1, p. 151-155, 2004.
Abstract: From July 1995 to August 1998, mycobacterial blood Cultures were obtained from 1032 HIV-infected patients seen at the Centro de Referncia e Treinamento de AIDS (CRTA), Hospital São Paulo (HSP), and Centro de Referncia de AIDS de Santos (CRAS). Overall, 179 episodes of mycobacteraemia were detected: 111 (62.0%) at CRTA, 50 (27.9%) at LISP, and 18 (10.1%) at CRAS. the frequency of positive Cultures declined sharply from 22.6%, in 1995 to 6.9% in 1998, consistent with the decrease in opportunistic infections following the publicly funded distribution of highly active anti retroviral therapy. in 1995, mycobacteraemia was more frequently due to Mycobacterium avium complex (59.2%) than Mycobacterium tuberculosis (28.6%), whereas in 1998 the relative frequencies were reversed (28.6 vs. 64.3% respectively), probably justified by the increased virulence of M. tuberculosis and the greater risk of invasive infection in less-immunocompromised patients, including patients unaware they are infected with HIV.
ISSN: 0950-2688
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