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Title: Serodiagnosis of chronic and acute Chagas' disease with Trypanosoma cruzi recombinant proteins: Results of a collaborative study in six Latin American countries
Authors: Umezawa, Eufrosina S.
Luquetti, Alejandro O.
Levitus, Gabriela
Ponce, Carlos
Ponce, Elisa
Henriquez, Diana
Revollo, Susana
Espinoza, Bertha
Sousa, Octavio
Khan, Baldip
Silveira, Jose Franco da [UNIFESP]
Universidade de São Paulo (USP)
Universidade Federal de São Paulo (UNIFESP)
Universidade Federal de Goiás (UFG)
Inst Invest Engn Genet & Biol Mol
Secretaria Salud
Univ Simon Bolivar
Univ Nacl Autonoma Mexico
Univ Panama
Issue Date: 1-Jan-2004
Publisher: Amer Soc Microbiology
Citation: Journal of Clinical Microbiology. Washington: Amer Soc Microbiology, v. 42, n. 1, p. 449-452, 2004.
Abstract: An enzyme-linked immunosorbent assay to diagnose Chagas' disease by a serological test was performed with Trypanosoma cruzi recombinant antigens (JL8, MAP, and TcPo). High sensitivity (99.4%) and specificity (99.3%) were obtained when JL8 was combined with MAP (JM) and tested with 150 serum samples from chagasic and 142 nonchagasic individuals. Moreover, JM also diagnosed 84.2% of patients in the acute phase of T. cruzi infection.
ISSN: 0095-1137
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Appears in Collections:Artigo

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