Please use this identifier to cite or link to this item: http://repositorio.unifesp.br/handle/11600/26933
Title: Efficacy and safety of flexible-dose oral sildenafil citrate (Viagra((R))) in the treatment of erectile dysfunction in Brazilian and Mexican men
Authors: Glina, S.
Bertero, E.
Claro, Joaquim [UNIFESP]
Damião, Ronaldo
Faria, Geraldo
Fregonesi, Adriano
Jaspersen, J.
Mendoza, Antonio
Mattos, Demerval
Rocha, Luiz Carlos
Sotomayor, Mariano
Teloken, Cláudio
Ureta, S.
Zonana, E.
Ugarte, F.
Hosp Albert Einstein
Torre Hosp Angeles del Pedregal
Fac Ciencias Med Santa Casa
Hosp Clin Cuiritiba
Universidade Estadual de Campinas (UNICAMP)
Clin Rio Claro
Univ Estadual Rio de Janeiro
Universidade Federal de São Paulo (UNIFESP)
Hosp Servidor Publ Estadual
Keywords: sildenafil
erectile dysfunction
impotence
penile erection
Issue Date: 1-Aug-2002
Publisher: Nature Publishing Group
Citation: International Journal of Impotence Research. London: Nature Publishing Group, v. 14, p. S27-S32, 2002.
Abstract: A 12-week, double-blind, placebo-controlled, multicenter study evaluated the efficacy and safety of flexible-dose sildenafil citrate (Viagra((R))) treatment (25, 50 or 100 mg) in Brazilian and Mexican men with erectile dysfunction (ED) of broad-spectrum etiology. Efficacy was assessed on the basis of responses to the 15-item International Index of Erectile Function (IIEF) questionnaire, completed at baseline and after 12 weeks of treatment. At end point, mean scores for all IIEF domains of sexual function (erectile function, orgasmic function, sexual desire, intercourse satisfaction and overall satisfaction) were significantly (P < 0.0001) higher in the sildenafil group (n = 109) than in the placebo group (n = 105). These findings confirm the significant increases in frequency of penetration and frequency of maintained erections reported previously. Sildenafil treatment was well tolerated. the most common adverse events were headache and flushing. in conclusion, sildenafil is a well-tolerated and effective treatment for ED of broad-spectrum etiology in Latin American men.
URI: http://repositorio.unifesp.br/handle/11600/26933
ISSN: 0955-9930
Other Identifiers: http://dx.doi.org/10.1038/sj.ijir.3900895
Appears in Collections:Em verificação - Geral

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