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|Title:||Nephrotic syndrome as a clinical manifestation of graft-versus-host disease (GVHD) in a marrow transplant recipient after cyclosporine withdrawal|
|Authors:||Oliveira, José Salvador Rodrigues de [UNIFESP]|
Bahia, Daniella Marcia Maranhão [UNIFESP]
Franco, Marcello Fabiano de [UNIFESP]
Kerbauy, José [UNIFESP]
Universidade Federal de São Paulo (UNIFESP)
bone marrow transplant
|Citation:||Bone Marrow Transplantation. Basingstoke: Stockton Press, v. 23, n. 1, p. 99-101, 1999.|
|Abstract:||GVHD is one of the most frequent complications of BMT and recently nephrotic syndrome (NS) has been described as a manifestation of chronic GVHD, Here, we present an AA patient who developed NS 1 year after BMT when cyclosporine was stopped. Renal biopsy showed focal sclerosis associated with membranous deposits. He also had other clinical manifestations of chronic GVHD: sicca-like syndrome and colestasis, After 15 days of CsA therapy, he experienced a remarkable improvement in the NS and GVHD as a whole. We comment on immunological mechanisms that could be involved in the pathogenesis of this manifestation.|
|Appears in Collections:||Em verificação - Geral|
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