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Title: Nephrotic syndrome as a clinical manifestation of graft-versus-host disease (GVHD) in a marrow transplant recipient after cyclosporine withdrawal
Authors: Oliveira, José Salvador Rodrigues de [UNIFESP]
Bahia, Daniella Marcia Maranhão [UNIFESP]
Franco, Marcello Fabiano de [UNIFESP]
Balda, C.
Stella, S.
Kerbauy, José [UNIFESP]
Universidade Federal de São Paulo (UNIFESP)
Keywords: nephrotic syndrome
bone marrow transplant
Issue Date: 1-Jan-1999
Publisher: Stockton Press
Citation: Bone Marrow Transplantation. Basingstoke: Stockton Press, v. 23, n. 1, p. 99-101, 1999.
Abstract: GVHD is one of the most frequent complications of BMT and recently nephrotic syndrome (NS) has been described as a manifestation of chronic GVHD, Here, we present an AA patient who developed NS 1 year after BMT when cyclosporine was stopped. Renal biopsy showed focal sclerosis associated with membranous deposits. He also had other clinical manifestations of chronic GVHD: sicca-like syndrome and colestasis, After 15 days of CsA therapy, he experienced a remarkable improvement in the NS and GVHD as a whole. We comment on immunological mechanisms that could be involved in the pathogenesis of this manifestation.
ISSN: 0268-3369
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Appears in Collections:Em verificação - Geral

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