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Title: Candida parapsilosis fungemia associated with implantable and semi-implantable central venous catheters and the hands of healthcare workers
Authors: Levin, A. S.
Costa, S. F.
Mussi, N. S.
Basso, M.
Sinto, S. I.
Machado, C.
Geiger, D. C.
Villares, MCB
Schreiber, A. Z.
Barone, A. A.
Branchini, MLM
Universidade de São Paulo (USP)
Universidade Federal de São Paulo (UNIFESP)
Universidade Estadual de Campinas (UNICAMP)
Issue Date: 1-Apr-1998
Publisher: Elsevier B.V.
Citation: Diagnostic Microbiology and Infectious Disease. New York: Elsevier B.V., v. 30, n. 4, p. 243-249, 1998.
Abstract: A cluster of six cases of fungemia among hematology, bone marrow transplant, and oncology patients was investigated in a case-control study (18 controls). the use of implantable and semi-implantable central venous catheters was significantly associated with cases (p = 0.016). the hands of three health care workers (HCWs) were positive for Candida parapsilosis. Electrophoretic karyotyping showed two profiles among patients and HCWs, and five among six unrelated strains. the profiles of two HCWs matched the ones of the patients they had handled. the patients' strains were moderate or strong slime producers, whereas none of the HCWs' were strong producers. in conclusion, our results indicated the occurrence of an outbreak C. parapsilosis fungemia related to long-term central venous catheters in which the hands of HCWs were implicated the amount of slime production might be associated with the pathogenicity of the strains. (C) 1998 Elsevier Science Inc.
ISSN: 0732-8893
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