Please use this identifier to cite or link to this item: https://repositorio.unifesp.br/handle/11600/25855
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dc.contributor.authorBorsatto, B.
dc.contributor.authorArruda, M. de
dc.contributor.authorSmith, C.
dc.contributor.authorGarcez, EMDM
dc.contributor.authorPeres, C. A.
dc.date.accessioned2016-01-24T12:30:32Z-
dc.date.available2016-01-24T12:30:32Z-
dc.date.issued1998-01-12
dc.identifierhttp://dx.doi.org/10.1016/S0047-6374(97)00122-X
dc.identifier.citationMechanisms of Ageing and Development. Clare: Elsevier Sci Ireland Ltd, v. 100, n. 1, p. 77-83, 1998.
dc.identifier.issn0047-6374
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/25855-
dc.description.abstractAge-related increases in the frequencies of cells with chromosome 21 loss and of polyploid cells were documented in short-term peripheral blood lymphocyte cultures from 54 patients with Down's syndrome (DS), ages 0 to 48 years. the polyploid data, together with previous work from this laboratory with non-DS subjects, suggest that this may be a useful indicator of aging in lymphocytes. (C) 1998 Elsevier Science Ireland Ltd.en
dc.format.extent77-83
dc.language.isoeng
dc.publisherElsevier B.V.
dc.relation.ispartofMechanisms of Ageing and Development
dc.rightsAcesso restrito
dc.subjectDown's syndromeen
dc.subjectchromosome 21en
dc.subjectagingen
dc.subjectpolyploidyen
dc.subjectPoisson regressionen
dc.titleAge-associated mosaicism and polyploidy in Down's syndromeen
dc.typeArtigo
dc.rights.licensehttp://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.description.affiliationUNIFESP, Escola Paulista Med, Disciplina Genet, Dept Morfol, BR-04023900 São Paulo, Brazil
dc.description.affiliationUnifespUNIFESP, Escola Paulista Med, Disciplina Genet, Dept Morfol, BR-04023900 São Paulo, Brazil
dc.identifier.doi10.1016/S0047-6374(97)00122-X
dc.description.sourceWeb of Science
dc.identifier.wosWOS:000072099300008
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