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|Title:||Age-associated mosaicism and polyploidy in Down's syndrome|
Arruda, M. de
Peres, C. A.
Universidade Federal de São Paulo (UNIFESP)
|Citation:||Mechanisms of Ageing and Development. Clare: Elsevier Sci Ireland Ltd, v. 100, n. 1, p. 77-83, 1998.|
|Abstract:||Age-related increases in the frequencies of cells with chromosome 21 loss and of polyploid cells were documented in short-term peripheral blood lymphocyte cultures from 54 patients with Down's syndrome (DS), ages 0 to 48 years. the polyploid data, together with previous work from this laboratory with non-DS subjects, suggest that this may be a useful indicator of aging in lymphocytes. (C) 1998 Elsevier Science Ireland Ltd.|
|Appears in Collections:||Em verificação - Geral|
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