Please use this identifier to cite or link to this item: https://repositorio.unifesp.br/handle/11600/1396
Title: Leucemia Mielóide Aguda t(8;21) após tratamento de hipertiroidismo com iodo radioativo: Leucemia secundária?
Other Titles: Acute Myeloid Leukemia t(8;21) after treatment for hyperthyroidism using radioactive iodine: Secondary Leukemia?
Authors: Bahia, Daniella Marcia Maranhão [UNIFESP]
Chauffaille, Maria de Lourdes Lopes Ferrari [UNIFESP]
Romeo, Maura S. [UNIFESP]
Dias-da-Silva, Magnus Régios [UNIFESP]
Kerbauy, José [UNIFESP]
Universidade Federal de São Paulo (UNIFESP)
Issue Date: 1-Apr-2002
Publisher: Associação Brasileira de Hematologia e Hemoterapia e Terapia Celular
Citation: Revista Brasileira de Hematologia e Hemoterapia. Associação Brasileira de Hematologia e Hemoterapia e Terapia Celular, v. 24, n. 2, p. 137-138, 2002.
Abstract: Acute leukemia following treatment with Iodine131 is a rare event. The possible carcinogenic effect of Iodine131 is still not clear and a large series of cases did not show an increased incidence of cancer. A case of AML t(8;21), three years after Iodine131 treatment for hyperthyroidism, is reported. Secondary AML with t(8;21) is described following exposure to drugs that target topoisomerase II and radiotherapy. The controversial potential of Iodine131 as a leukemogenic agent and the fact that t(8;21) is also found in de-novo AML, emphasize the problem in establishing a relationship between these events although this potential can not be ruled out.
URI: http://repositorio.unifesp.br/handle/11600/1396
ISSN: 1516-8484
Other Identifiers: http://dx.doi.org/10.1590/S1516-84842002000200010
Appears in Collections:Em verificação - Geral

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