Systematic reviews on leptospirosis

Systematic reviews on leptospirosis

Autor Guidugli, Fabio Google Scholar
Castro, Aldemar Araujo Autor UNIFESP Google Scholar
Atallah, Álvaro Nagib Autor UNIFESP Google Scholar
Instituição Universidade Federal de São Paulo (UNIFESP)
Resumo OBJECTIVES: To find the existing clinical evidence on interventions for leptospirosis. The objective is to evaluate the effectiveness and safety of any intervention on leptospirosis through systematic reviews of randomized controlled trials (RCTs).DATA SOURCE: The sources of studies used (where there were no limitations concerning language, date, or other restrictions) were: EMBASE, LILACS, MEDLINE, the Cochrane Controlled Clinical Trials Database, and the Cochrane Hepato-Biliary Group Randomized Trials register.SELECTION OF STUDIES: Type of Study: All systematic reviews of randomized controlled trials. Participants: patients with clinical and/or laboratorial diagnosis of leptospirosis, and subjects potencially exposed to leptospirosis as defined by the authors Interventions: any intervention for leptospirosis (as antibiotics or vaccines for prevention or treatment).DATA COLLECTION: The assessment will be independently made by the reviewers and cross-checked. The external validity was assessed by analysis of: studies, interventions, and outcomes.DATA SYNTHESIS: Located 163 studies using the search strategy described above, at the electronic databases above. Only 2 hits were selected, which are protocols of systematic reviews of Cochrane Collaboration, and not full reviews. One of the protocols evaluates antibiotics for treatment, and the other evaluates antibiotics for prevention of leptospirosis.CONCLUSIONS: There were not complete systematic reviews on interventions for leptospirosis. Any interventions for leptospirosis, such as prevention and treatment remains unclear for guidelines and practice.
Palavra-chave Leptospirosis
Treatment
Prevention
Systematic review
Meta-analysis
Idioma Inglês
Data de publicação 2000-02-01
Publicado em Revista do Instituto de Medicina Tropical de São Paulo. Instituto de Medicina Tropical, v. 42, n. 1, p. 47-49, 2000.
ISSN 0036-4665 (Sherpa/Romeo)
Publicador Instituto de Medicina Tropical
Extensão 47-49
Fonte http://dx.doi.org/10.1590/S0036-46652000000100008
Direito de acesso Acesso aberto Open Access
Tipo Artigo
SciELO S0036-46652000000100008 (estatísticas na SciELO)
Endereço permanente http://repositorio.unifesp.br/handle/11600/908

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