Intima-media thickness evaluation by B-mode ultrasound: Correlation with blood pressure levels and cardiac structures

Intima-media thickness evaluation by B-mode ultrasound: Correlation with blood pressure levels and cardiac structures

Autor Plavnik, Frida Liane Autor UNIFESP Google Scholar
Ajzen, Sergio Aron Autor UNIFESP Google Scholar
Kohlmann Junior, Osvaldo Autor UNIFESP Google Scholar
Tavares, Agostinho Autor UNIFESP Google Scholar
Zanella, Maria Teresa Autor UNIFESP Google Scholar
Ribeiro, A.b. Autor UNIFESP Google Scholar
Ramos, Oswaldo Luiz Autor UNIFESP Google Scholar
Instituição Universidade Federal de São Paulo (UNIFESP)
Resumo The aim of this study was to analyze the thickness of the intima-media complex (IMC) using a noninvasive method. The carotid and femoral common arteries were evaluated by noninvasive B-mode ultrasound in 63 normotensive and in 52 hypertensive subjects and the thickness of the IMC was tested for correlation with blood pressure, cardiac structures and several clinical and biological parameters. The IMC was thicker in hypertensive than in normotensive subjects (0.67 ± 0.13 and 0.62 ± 0.16 vs 0.54 ± 0.09 and 0.52 ± 0.11 mm, respectively, P<0.0001). In normotensive patients, the simple linear regression showed significant correlations between IMC and age, body mass index and 24-h systolic blood pressure for both the carotid and femoral arteries. In hypertensives the carotid IMC was correlated with age and 24-h systolic blood pressure while femoral IMC was correlated only with 24-h diastolic blood pressure. Forward stepwise regression showed that age, body mass index and 24-h systolic blood pressure influenced the carotid IMC relationship (r2 = 0.39) in normotensives. On the other hand, the femoral IMC relationship was influenced by 24-h systolic blood pressure and age (r2 = 0.40). In hypertensives, age and 24-h systolic blood pressure were the most important determinants of carotid IMC (r2 = 0.37), while femoral IMC was influenced only by 24-h diastolic blood pressure (r2 = 0.10). There was an association between carotid IMC and echocardiographic findings in normotensives, while in hypertensives only the left posterior wall and interventricular septum were associated with femoral IMC. We conclude that age and blood pressure influence the intima-media thickness, while echocardiographic changes are associated with the IMC.
Palavra-chave arterial thickness
B-mode ultrasound
24-ABPM
cardiac structures
Idioma Inglês
Data de publicação 2000-01-01
Publicado em Brazilian Journal of Medical and Biological Research. Associação Brasileira de Divulgação Científica, v. 33, n. 1, p. 55-64, 2000.
ISSN 0100-879X (Sherpa/Romeo, fator de impacto)
Publicador Associação Brasileira de Divulgação Científica
Extensão 55-64
Fonte http://dx.doi.org/10.1590/S0100-879X2000000100008
Direito de acesso Acesso aberto Open Access
Tipo Artigo
Web of Science WOS:000085031800008
SciELO S0100-879X2000000100008 (estatísticas na SciELO)
Endereço permanente http://repositorio.unifesp.br/handle/11600/894

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