Low-level laser therapy modulates musculoskeletal loss in a skin burn model in rats

Low-level laser therapy modulates musculoskeletal loss in a skin burn model in rats

Autor Martins, Francielle Google Scholar
Renno, Ana Claudia Muniz Autor UNIFESP Google Scholar
De Oliveira, Flavia Autor UNIFESP Google Scholar
Minatel, Natália Peruchi Google Scholar
Bortolin, Jeferson André Google Scholar
Quintana, Hananiah Tardivo Google Scholar
Aveiro, Mariana Chaves Autor UNIFESP Google Scholar
Instituição Ministry of Science, Technology and Inovation National Council of Scientific and Technological Development Institutional Program for Scientific Initiation
Universidade Federal de São Paulo (UNIFESP)
Resumo PURPOSE: To investigate the effectiveness of low-level laser therapy (LLLT) on gastrocnemius muscle morphology and Myod imunoexpression in a model of dorsal burn in rats. METHODS: Sixteen male Wistar rats were distributed into two groups: control group (CG): rats submitted to scald burn injury without treatment and laser treated group (LG): rats submitted to scald burn injury and treated with laser therapy. Fourteen days post-surgery, gastrocnemius muscle was evaluated being the specimens stained with HE and morphometric data was evaluated. MyoD expression was assessed by immunohistochemistry. RESULTS: The results showed that laser treated animals presented more organized tissue morphology compared to the non-treated animals, with a higher number of nucleus in the fibers. Also, the cross sectional area of the fibers and the MyoD immunoexpression in the laser treated groups was higher. CONCLUSION: Low-level laser therapy had positive effects on gastrocnemius muscle, improving tissue muscle morphology, increasing cross sectional area and MyoD immunoexpression.
Palavra-chave Burns
Laser Therapy, Low-Level
MyoD Protein
Rats
Idioma Inglês
Financiador Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
Data de publicação 2015-02-01
Publicado em Acta Cirurgica Brasileira. Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia, v. 30, n. 2, p. 94-99, 2015.
ISSN 0102-8650 (Sherpa/Romeo, fator de impacto)
Publicador Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia
Extensão 94-99
Fonte http://dx.doi.org/10.1590/S0102-86502015002000002
Direito de acesso Acesso aberto Open Access
Tipo Artigo
Web of Science WOS:000350333000002
SciELO S0102-86502015000200094 (estatísticas na SciELO)
Endereço permanente http://repositorio.unifesp.br/handle/11600/8793

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