The effects of low level laser therapy on injured skeletal muscle

The effects of low level laser therapy on injured skeletal muscle

Autor Renno, Ana Claudia Muniz Autor UNIFESP Google Scholar
Assis, Lívia Autor UNIFESP Google Scholar
Peres, Beatriz Autor UNIFESP Google Scholar
Rodrigues, Natalia Camargo Google Scholar
Brunelli, Roberta de Matos Google Scholar
Toma, Renata Luri Autor UNIFESP Google Scholar
Medalha, Carla Christina Autor UNIFESP Google Scholar
Ribeiro, Daniel Araki Autor UNIFESP Google Scholar
Instituição Universidade Federal de São Paulo (UNIFESP)
Universidade Federal de São Carlos Centro de Ciências Biológicas e da Saúde Departamento de Fisioterapia
Resumo The main purpose of the present study was to investigate the effects of low-level laser therapy (LLLT) used in two different fluencies on injured skeletal muscle after cryolesion by means of histopathological analysis and immunohistochemistry for COX-2. A total of sixty male Wistar rats were randomly distributed into three groups: injured animals without any treatment; 808 nm laser treated group, at 10 J/cm² and 808 nm laser treated group, at 50 J/cm². Each group was divided into two different subgroups (n=10) on days 6 and 13 post-injury. The results showed that the animals irradiated with laser at 10 J/cm² or 50 J/cm² presented the areas with cell infiltrate and pointed out to minor and mild areas with destroyed zones compared with the control group. Also, a COX-2 downregulation was noticed in the groups exposed to laser at two fluences evaluated in this study. Significant statistically differences (p<0.05) were noticed to collagen deposition in the laser treated animals, with the fluence of 50 J/cm² when compared to the other groups on day 13 post-surgery. Taken together, these results suggested that laser therapy could have positive effects on muscle repair in the rats after cryolesion.
Palavra-chave low level laser therapy
rat
muscle repair
COX-2
Idioma Inglês
Financiador Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
Data de publicação 2014-02-01
Publicado em Brazilian Archives of Biology and Technology. Instituto de Tecnologia do Paraná - Tecpar, v. 57, n. 1, p. 48-54, 2014.
ISSN 1516-8913 (Sherpa/Romeo, fator de impacto)
Publicador Instituto de Tecnologia do Paraná - Tecpar
Extensão 48-54
Fonte http://dx.doi.org/10.1590/S1516-89132014000100008
Direito de acesso Acesso aberto Open Access
Tipo Artigo
Web of Science WOS:000332125000008
SciELO S1516-89132014000100008 (estatísticas na SciELO)
Endereço permanente http://repositorio.unifesp.br/handle/11600/8232

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