Oxandrolone use in adult burn patients. Systematic review and meta-analysis

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dc.contributor.author Real, Daniel Sundfeld Spiga [UNIFESP]
dc.contributor.author Reis, Rodrigo Pacheco
dc.contributor.author Piccolo, Monica Sarto
dc.contributor.author Okamoto, Regina H.
dc.contributor.author Gragnani, Alfredo [UNIFESP]
dc.contributor.author Ferreira, Lydia Masako [UNIFESP]
dc.date.accessioned 2015-06-14T13:46:53Z
dc.date.available 2015-06-14T13:46:53Z
dc.date.issued 2014-01-01
dc.identifier http://dx.doi.org/10.1590/S0102-86502014001700013
dc.identifier.citation Acta Cirurgica Brasileira. Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia, v. 29, p. 68-76, 2014.
dc.identifier.issn 0102-8650
dc.identifier.uri http://repositorio.unifesp.br/handle/11600/8191
dc.description.abstract PURPOSE:This study is a systematic literature review and meta-analysis concerning the use of a testosterone synthetic analog, oxandrolone, and its use in severe adult burns.METHODS:Randomized prospective clinical studies, in English, Portuguese or Spanish, were sought on the following databases: MEDLINE, COCHRANE, EMBASE and LILACS. There was no restriction in relation to the publication date.RESULTS: This search produced 24 studies on MEDLINE and twelve articles were presented on the COCHRANE database .Sixteen were excluded due to the title not being related to this search or by including children. Of the eigth residual studies, after adaptation to the inclusion criteria, only four were selected. After analyzing the results, two were discarded since they did not present adequate patient characterization and the facts on these articles were analyzed differently from the others, hindering the meta-analysis.CONCLUSION:The analysis of the available data demonstrated significant benefits (p<0.05) considering lesser loss of corporal mass, lesser nitrogen loss, and shorter donor area healing time, when Oxandrolone was used, comparatively with the control group (placebo or not). en
dc.format.extent 68-76
dc.language.iso eng
dc.publisher Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia
dc.relation.ispartof Acta Cirurgica Brasileira
dc.rights Acesso aberto
dc.subject Oxandrolone en
dc.subject Burns en
dc.subject Adults en
dc.subject Systematic review en
dc.subject Meta-analysis en
dc.title Oxandrolone use in adult burn patients. Systematic review and meta-analysis en
dc.type Artigo
dc.contributor.institution Universidade Federal de São Paulo (UNIFESP)
dc.description.affiliation Federal University of São Paulo
dc.description.affiliationUnifesp UNIFESP
dc.identifier.file S0102-86502014001500068.pdf
dc.identifier.scielo S0102-86502014001500068
dc.identifier.doi 10.1590/S0102-86502014001700013
dc.description.source SciELO
dc.identifier.wos WOS:000344466300014



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