A gastrocnemius heterotopical transplant model with end-to-side neurorraphy

A gastrocnemius heterotopical transplant model with end-to-side neurorraphy

Autor Jaeger, Marcos Ricardo de Oliveira Google Scholar
Braga Silva, Jefferson Autor UNIFESP Google Scholar
Bain, James Google Scholar
Ely, Pedro Bins Google Scholar
Pires, Jefferson André Google Scholar
Ferreira, Lydia Masako Autor UNIFESP Google Scholar
Instituição Universidade Federal de São Paulo (UNIFESP)
Pontifícia Universidade Católica do Rio Grande do Sul Hospital São Lucas
McMaster University
Federal University of Health Science
Federal University of Pelotas Departament of Surgery
Resumo PURPOSE: To present an animal model to assess the effects of end-to-side innervation in the heterotopically transplanted model with reduced chances of neural contamination.METHODS:The medial portion of the gastrocnemius muscle in wistar male rats was isolated and its pedicle dissected and performed a flap in the abdominal portion. To prevent neural contamination in the abdominal region, the muscle was wrapped with a Goretex(r) sheet. The specimens were divided into 2 groups (G). In G1 was performed an end-to-end suture between tibial nerve of the gastrocnemius and femoral motor nerve and between the saphenous sensory nerve and the motor nerve. In G2 was performed a end-to-side suture between the tibial nerve and the motor femoral and between the tibial nerve and saphenous motor nerve. The specimens were evaluated 60 days later to check the structure of the neurorraphy. Sections were obtained proximal and distal to the coaptation site.RESULTS:The medial gastrocnemius muscle had the advantage of maintaining visible mass after 60 days. No disruption of the coaptation site was found. No major injury to the donor nerve was seen in group 2.CONCLUSION: The proposed model is simple, reproduciple and prevent the neural contamination in the flap in end-to-side suture.
Palavra-chave Animal model
Mycrosurgery
Rats
Idioma Inglês
Data de publicação 2014-01-01
Publicado em Acta Cirurgica Brasileira. Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia, v. 29, p. 50-54, 2014.
ISSN 0102-8650 (Sherpa/Romeo, fator de impacto)
Publicador Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia
Extensão 50-54
Fonte http://dx.doi.org/10.1590/S0102-8650201400140010
Direito de acesso Acesso aberto Open Access
Tipo Artigo
Web of Science WOS:000342065300011
SciELO S0102-86502014001400011 (estatísticas na SciELO)
Endereço permanente http://repositorio.unifesp.br/handle/11600/8155

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