Neovascularization after surgical exposure of rat external jugular vein endothelium

Neovascularization after surgical exposure of rat external jugular vein endothelium

Autor Nascimento, José Francimário Bezerra Do Autor UNIFESP Google Scholar
Pitta, Guilherme Brandão Benjamin Google Scholar
Miranda Junior, Fausto Autor UNIFESP Google Scholar
Instituição Universidade Federal de São Paulo (UNIFESP)
University of Health Sciences of Alagoas Department of Surgery
Resumo PURPOSE: To investigate the neovascularization after exposure of the external jugular venous endothelium in an experimental model. METHODS: The sample was composed of 60 male rats of Wistar OUT B breed provided by animal colony of the Medicine College of Juazeiro do Norte, weighing 250 to 350g, aged 90-120 days. Randomized study in OUT B Wistar rats, open, with 60 days duration. The animals were distributed into three groups of 20 specimens and were subjected to the following: Group 1: neck incision with dissection, ligation and section of the external jugular vein. Group 2: neck incision with dissection and ligation of the external jugular vein. Group 3: cervicotomy without dissection of the external jugular vein without ligation or section. The animals were sacrificed, half of them in 30 days and the other half within 60 days. The material in block harvested from the operated site were sectioned and stained for immunohistochemistry with CD34 marker. RESULTS: Neovascularization occurred with level of significance when compared group 1 to group 3 at 30 days (p=0.0076) and the same occurred at 60 days (p=0.0001) (Newman-Keuls test). CONCLUSION: The group with exposure of the venous endothelium showed a significant increase of neovascularization when compared with other groups.
Palavra-chave Neovascularization
Jugular Veins
Endothelium
Rats
Idioma Inglês
Data de publicação 2013-12-01
Publicado em Acta Cirurgica Brasileira. Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia, v. 28, n. 12, p. 820-823, 2013.
ISSN 0102-8650 (Sherpa/Romeo, fator de impacto)
Publicador Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia
Extensão 820-823
Fonte http://dx.doi.org/10.1590/S0102-86502013001200003
Direito de acesso Acesso aberto Open Access
Tipo Artigo
Web of Science WOS:000328649900003
SciELO S0102-86502013001200003 (estatísticas na SciELO)
Endereço permanente http://repositorio.unifesp.br/handle/11600/8078

Exibir registro completo




Arquivo

Nome: S0102-86502013001200003.pdf
Tamanho: 1.373MB
Formato: PDF
Descrição:
Abrir arquivo

Este item está nas seguintes coleções

Buscar


Navegar

Minha conta