Vitamin D and its relation to bone mineral density in postmenopause women

Vitamin D and its relation to bone mineral density in postmenopause women

Alternative title Vitamina D e sua relação com a densidade mineral óssea em mulheres na pós-menopausa
Author Labronici, Pedro José Autor UNIFESP Google Scholar
Blunck, Saulo Santos Google Scholar
Lana, Flavius Ribeiro Google Scholar
Esteves, Bruno Bandeira Google Scholar
Franco, José Sergio Google Scholar
Fukuyama, Junji Miller Google Scholar
Pires, Robinson Esteves Santos Google Scholar
Institution Universidade Federal de São Paulo (UNIFESP)
Hospital Santa Teresa Clinical Head of the Orthopedics and Traumatology Service of Prof. Dr. Donato D'Ângelo
Hospital Santa Teresa Clinical Head of the Orthopedics and Traumatology Service of Prof. Dr. Donato D'ngelo
UFRJ Department of the Medical School
Hospital Geral Vila Penteado
Universidade Federal de Minas Gerais Department of the Locomotor System
Hospital Felício Rocho
Abstract OBJECTIVE:Compare the level of vitamin D with the bone mineral density (BMD) in postmenopausal women, with or without fractures.METHODS:250 women with mean age of 71.1 were evaluated. The serum levels of vitamin D considered sufficient were ≥ 30 ng/mL, insufficient between 20 and 30 ng/mL and deficient < 20 ng/mL. The bone mineral density was measured and considered osteopenia when T value total of lumbar spine or hip was between -1 and -2.5 and osteoporosis < 2.5. The patients with fractures accounted for 25.2%.RESULTS:There was no significant difference in the vitamin D (ng/mL) levels among the age groups (p = 0.25), the levels of fractures (p = 0.79) and the levels of BMD (p = 0.76).CONCLUSION:82% of the patients presented deficient and insufficient blood levels of vitamin D. Ours results showed any significant correlation between vitamin D levels and bone mineral density after adjusting for age.

OBJETIVO : Comparar o nível de vitamina D com a densidade mineral óssea (DMO) em mulheres na pós-menopausa, com ou sem fraturas.MÉTODOS : Foram avaliadas 250 mulheres com idade média de 71,1 anos. Os níveis séricos de vitamina D foram considerados normais quando ≥ 30 ng/mL, insuficientes entre 20 e 30 ng/mL e deficientes < 20 ng/mL. A DMO foi medida e considerada osteopenia quando o valor total T da coluna lombar ou do quadril estava entre -1 e -2,5 e osteoporose quando < -2,5. As pacientes com fratura somavam 25,2%. RESULTADOS : Não existiu diferença significativa na dosagem de vitamina D (ng/mL) entre as faixas etárias (p = 0,25), os níveis de fratura (p = 0,79) e os níveis da DMO (p = 0,76).CONCLUSÃO : Das pacientes, 82% apresentaram níveis séricos de vitamina D deficientes e insuficientes. Nossos resultados não demonstraram correlação significativa entre os níveis de vitamina D e DMO com a idade..
Keywords Vitamin D
Osteoporosis
Bone density
Fractures, bone
Vitamina D
Osteoporose
Densidade óssea
Fraturas ósseas
Language English
Date 2013-06-01
Published in Revista Brasileira de Ortopedia. Sociedade Brasileira de Ortopedia e Traumatologia, v. 48, n. 3, p. 228-235, 2013.
ISSN 0102-3616 (Sherpa/Romeo)
Publisher Sociedade Brasileira de Ortopedia e Traumatologia
Extent 228-235
Origin http://dx.doi.org/10.1016/j.rbo.2012.07.004
Access rights Open access Open Access
Type Article
SciELO ID S0102-36162013000300228 (statistics in SciELO)
URI http://repositorio.unifesp.br/handle/11600/7790

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