Human coronavirus ocurrence in different populations of São Paulo: a comprehensive nine-year study using a pancoronavirus RT-PCR assay

Mostrar registro simples Cabeça, Tatiane Karen [UNIFESP] Passos, Ana Maria [UNIFESP] Granato, Celso Francisco Hernandes [UNIFESP] Bellei, Nancy Cristina Junqueira [UNIFESP] 2015-06-14T13:45:10Z 2015-06-14T13:45:10Z 2013-01-01
dc.identifier.citation Brazilian Journal of Microbiology. Sociedade Brasileira de Microbiologia, v. 44, n. 1, p. 335-339, 2013.
dc.identifier.issn 1517-8382
dc.description.abstract Human coronaviruses (HCoVs) are considered one of the most common respiratory viruses associated with respiratory tract illnesses. An emergent human coronavirus was identified as the causal agent of an epidemic of severe acute respiratory syndrome (SARS) during 2002-2003. The severity of the disease combined with its rapid spread requires the continuous surveillance of coronaviruses in worldwide populations. Epidemiological and clinical data of HCoVs infectious in the Brazilian population are scarce and restricted to one or two groups of patients. Our study aimed to investigate retrospectively the presence of HCoVs in different populations of São Paulo presenting acute respiratory tract infections (ARIs) during the years of 2001-2010. A pancoronavirus RT-PCR was performed in this study. Coronaviruses were detected in 126 (11.5%) of 1,087 specimens. Peaks detection frequency was observed during 2002-2004 and 2008-2009, with the highest detection in 2008. The prevalence of HCoVs was higher among children with heart diseases (24.6%), patients under stem cell transplantation program (24.3%) and renal transplanted patients (20.2%). Coryza, cough and fever were the most common symptoms at presentation of positive cases and wheezing, a lower respiratory tract infection symptom was reported by 12% of the total, and 27% of high at-risk patients. HCoVs may have an important role among patients with underlying conditions and transplanted ones. en
dc.description.sponsorship Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.format.extent 335-339
dc.language.iso eng
dc.publisher Sociedade Brasileira de Microbiologia
dc.relation.ispartof Brazilian Journal of Microbiology
dc.rights Acesso aberto
dc.subject human coronaviruses en
dc.subject epidemiology en
dc.subject respiratory tract illness en
dc.subject pancoronavirus RT-PCR en
dc.title Human coronavirus ocurrence in different populations of São Paulo: a comprehensive nine-year study using a pancoronavirus RT-PCR assay en
dc.type Artigo
dc.contributor.institution Universidade Federal de São Paulo (UNIFESP)
dc.description.affiliation Universidade Federal de São Paulo (UNIFESP) Department of Medicine Clinical Virology Laboratory
dc.description.affiliationUnifesp UNIFESP, Department of Medicine Clinical Virology Laboratory
dc.identifier.file S1517-83822013000100049.pdf
dc.identifier.scielo S1517-83822013000100049
dc.identifier.doi 10.1590/S1517-83822013000100049
dc.description.source SciELO
dc.identifier.wos WOS:000323575600049

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