Emergence of Klebsiella pneumoniae-producing KPC-2 carbapenemase in Paraíba, Northeastern Brazil

Emergence of Klebsiella pneumoniae-producing KPC-2 carbapenemase in Paraíba, Northeastern Brazil

Author Fehlberg, Lorena Cristina Corrêa Autor UNIFESP Google Scholar
Carvalho, Albalucia M.c. Google Scholar
Campana, Eloiza Helena Autor UNIFESP Google Scholar
Gontijo-Filho, Paulo P. Google Scholar
Gales, Ana Cristina Autor UNIFESP Google Scholar
Institution Universidade Federal de São Paulo (UNIFESP)
Universidade Federal da Paraíba Hospital Universitário Lauro Wanderley
Universidade Federal de Uberlândia Biological Sciences Institute
Abstract The emergence of KPC-2 producing K. pneumoniae in hospitalized patients at the intensive care unit (ICU) of a teaching hospital located in the city of João Pessoa, Paraíba, Brazil, is reported. Seven carbapenem-resistant K. pneumoniae recovered from different body sites of infection were analyzed. Most isolates showed a multidrug-resistance phenotype. Genotypic analysis demonstrated the presence of two genotypes, with the predominance of genotype A, which belongs to ST 437. These isolates also carry the encoding genes of five other betalactamases.
Keywords Beta-lactam resistance
Modified Hodge test
Carbapenem resistance
Enterobacteriaceae
Language English
Date 2012-12-01
Published in Brazilian Journal of Infectious Diseases. Brazilian Society of Infectious Diseases, v. 16, n. 6, p. 577-580, 2012.
ISSN 1413-8670 (Sherpa/Romeo, impact factor)
Publisher Brazilian Society of Infectious Diseases
Extent 577-580
Origin http://dx.doi.org/10.1016/j.bjid.2012.07.001
Access rights Open access Open Access
Type Article
Web of Science ID WOS:000312680400013
SciELO ID S1413-86702012000600013 (statistics in SciELO)
URI http://repositorio.unifesp.br/handle/11600/7421

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