Wound-healing and benzodiazepines: does sleep play a role in this relationship?

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dc.contributor.author Egydio, Flavia [UNIFESP]
dc.contributor.author Pires, Gabriel Natan [UNIFESP]
dc.contributor.author Tufik, Sergio [UNIFESP]
dc.contributor.author Andersen, Monica Levy [UNIFESP]
dc.date.accessioned 2015-06-14T13:44:49Z
dc.date.available 2015-06-14T13:44:49Z
dc.date.issued 2012-07-01
dc.identifier http://dx.doi.org/10.6061/clinics/2012(07)20
dc.identifier.citation Clinics. Faculdade de Medicina / USP, v. 67, n. 7, p. 827-830, 2012.
dc.identifier.issn 1807-5932
dc.identifier.uri http://repositorio.unifesp.br/handle/11600/7193
dc.description.abstract Patients who have suffered burns frequently experience psychological consequences, among which anxiety disorders are prominent. Benzodiazepines are commonly administered to treat these symptoms. The effects of benzodiazepines on healing may not be direct but rather are modulated by alterations of the sleep architecture. This hypothesis is supported by studies that demonstrate the effects of benzodiazepines on the immune system and the inflammatory profile under both normal sleep conditions and during sleep deprivation, particularly rapid eye movement sleep deprivation. en
dc.description.sponsorship Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.description.sponsorship Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.description.sponsorship Associacao Fundo de Incentivo a Pesquisa (AFIP)
dc.description.sponsorship Fundacao de Amparo a Pesquisa do Estado de Sao Paulo-FAPESP (CEPID)
dc.format.extent 827-830
dc.language.iso eng
dc.publisher Faculdade de Medicina / USP
dc.relation.ispartof Clinics
dc.rights Acesso aberto
dc.subject Benzodiazepines en
dc.subject Sleep Deprivation en
dc.subject Wound Healing en
dc.subject Burns en
dc.subject Immune System en
dc.title Wound-healing and benzodiazepines: does sleep play a role in this relationship? en
dc.type Artigo
dc.contributor.institution Universidade Federal de São Paulo (UNIFESP)
dc.description.affiliation Universidade Federal de São Paulo (UNIFESP) Departamento de Psicobiologia
dc.description.affiliationUnifesp UNIFESP, Depto. de Psicobiologia
dc.description.sponsorshipID 2011/14462-0 e 2010/14768-0
dc.description.sponsorshipID 98/14303-3
dc.identifier.file S1807-59322012000700020.pdf
dc.identifier.scielo S1807-59322012000700020
dc.identifier.doi 10.6061/clinics/2012(07)20
dc.description.source SciELO
dc.identifier.wos WOS:000307723100020


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