Transcranial sonography in Parkinson's disease

Transcranial sonography in Parkinson's disease

Alternative title Ultrassonografia transcraniana na doença de Parkinson
Author Bor-seng-shu, Edson Google Scholar
Pedroso, José Luiz Autor UNIFESP Google Scholar
Andrade, Daniel Ciampi De Google Scholar
Barsottini, Orlando Graziani Povoas Autor UNIFESP Google Scholar
Andrade, Luiz Augusto Franco de Autor UNIFESP Google Scholar
Barbosa, Egberto Reis Google Scholar
Teixeira, Manoel Jacobsen Google Scholar
Institution Universidade de São Paulo (USP)
Hospital Israelita Albert Einstein
Universidade Federal de São Paulo (UNIFESP)
Hospital Israelita Albert Einstein Instituto do Cérebro
Abstract Transcranial sonography has become a useful tool in the differential diagnosis of parkinsonian syndromes. This is a non-invasive, low cost procedure. The main finding on transcranial sonography in patients with idiopathic Parkinson's disease is an increased echogenicity of the mesencephalic substantia nigra region. This hyperechogenicity is present in more than 90% of cases, and reflects a dysfunction in the dopaminergic nigrostriatal pathway. This study discussed how the hyperechogenicity of the substantia nigra may facilitate the differential diagnosis of parkinsonian syndromes.

A ultrassonografia transcraniana tem se tornado ferramenta útil no diagnóstico diferencial das síndromes parkinsonianas. Trata-se de um método não invasivo e de baixo custo. O principal achado da ultrassonografia transcraniana em pacientes com doença de Parkinson idiopática é o aumento da ecogenicidade, ou hiperecogenicidade, na região da substância negra mesencefálica, presente em mais de 90% dos casos, o que reflete disfunção da via dopaminérgica nigroestriatal. O presente trabalho abordou como a hiperecogenicidade da substância negra pode auxiliar no diagnóstico diferencial das síndromes parkinsonianas.
Keywords Parkinson disease
Ultrasonography, doppler, transcranial
Diagnosis, differential
Doença de Parkinson
Ultrassonografia doppler transcraniana
Diagnóstico diferencial
Language English
Date 2012-06-01
Published in Einstein (São Paulo). Instituto Israelita de Ensino e Pesquisa Albert Einstein, v. 10, n. 2, p. 242-246, 2012.
ISSN 1679-4508 (Sherpa/Romeo)
Publisher Instituto Israelita de Ensino e Pesquisa Albert Einstein
Extent 242-246
Origin http://dx.doi.org/10.1590/S1679-45082012000200022
Access rights Open access Open Access
Type Article
SciELO ID S1679-45082012000200022 (statistics in SciELO)
URI http://repositorio.unifesp.br/handle/11600/7106

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