Full-length genomic sequence of hepatitis B virus genotype C2 isolated from a native Brazilian patient

Full-length genomic sequence of hepatitis B virus genotype C2 isolated from a native Brazilian patient

Autor Alvarado-Mora, Mónica Viviana Google Scholar
Santana, Rúbia Anita Ferraz Google Scholar
Sitnik, Roberta Google Scholar
Ferreira, Paulo Roberto Abrão Autor UNIFESP Google Scholar
Mangueira, Cristóvão Luis Pitangueiras Google Scholar
Carrilho, Flair José Google Scholar
Pinho, João Renato Rebello Google Scholar
Instituição Universidade de São Paulo (USP)
Hospital Israelita Albert Einstein Departamento de Patologia Clínica
Universidade Federal de São Paulo (UNIFESP)
Resumo The hepatitis B virus (HBV) is among the leading causes of chronic hepatitis, cirrhosis and hepatocellular carcinoma. In Brazil, genotype A is the most frequent, followed by genotypes D and F. Genotypes B and C are found in Brazil exclusively among Asian patients and their descendants. The aim of this study was to sequence the entire HBV genome of a Caucasian patient infected with HBV/C2 and to infer the origin of the virus based on sequencing analysis. The sequence of this Brazilian isolate was grouped with four other sequences described in China. The sequence of this patient is the first complete genome of HBV/C2 reported in Brazil.
Palavra-chave hepatitis B virus
genotype C2
China
Bayesian analyses
complete genome
Brazilian patient
Idioma Inglês
Data de publicação 2011-06-01
Publicado em Memórias do Instituto Oswaldo Cruz. Instituto Oswaldo Cruz, Ministério da Saúde, v. 106, n. 4, p. 495-498, 2011.
ISSN 0074-0276 (Sherpa/Romeo, fator de impacto)
Publicador Instituto Oswaldo Cruz, Ministério da Saúde
Extensão 495-498
Fonte http://dx.doi.org/10.1590/S0074-02762011000400017
Direito de acesso Acesso aberto Open Access
Tipo Artigo
Web of Science WOS:000292402300017
SciELO S0074-02762011000400017 (estatísticas na SciELO)
Endereço permanente http://repositorio.unifesp.br/handle/11600/6452

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