Brazilian Guidelines for transcranial doppler in children and adolescents with sickle cell disease

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dc.contributor.author Lobo, Clarisse Lopes de Castro
dc.contributor.author Cançado, Rodolfo Delfini
dc.contributor.author Leite, Ana Claudia Celestino Bezerra
dc.contributor.author Anjos, Ana Claudia Mendonça dos
dc.contributor.author Pinto, Ana Cristina Silva
dc.contributor.author Matta, Andre Palma da Cunha
dc.contributor.author Silva, Célia Maria
dc.contributor.author Silva, Gisele Sampaio [UNIFESP]
dc.contributor.author Friedrisch, João Ricardo
dc.contributor.author Braga, Josefina Aparecida Pellegrini [UNIFESP]
dc.contributor.author Lange, Marcos Christiano
dc.contributor.author Figueiredo, Maria Stella [UNIFESP]
dc.contributor.author Rugani, Marília Álvares
dc.contributor.author Veloso, Orlando
dc.contributor.author Moura, Patrícia Gomes
dc.contributor.author Cortez, Paulo Ivo
dc.contributor.author Adams, Robert
dc.contributor.author Gualandro, Sandra Fátima Menosi
dc.contributor.author Castilho, Shirley Lopes de
dc.contributor.author Thomé, Ursula
dc.contributor.author Zetola, Viviane Flumignan
dc.date.accessioned 2015-06-14T13:42:54Z
dc.date.available 2015-06-14T13:42:54Z
dc.date.issued 2011-02-01
dc.identifier http://dx.doi.org/10.5581/1516-8484.20110014
dc.identifier.citation Revista Brasileira de Hematologia e Hemoterapia. Associação Brasileira de Hematologia e Hemoterapia e Terapia Celular, v. 33, n. 1, p. 43-48, 2011.
dc.identifier.issn 1516-8484
dc.identifier.uri http://repositorio.unifesp.br/handle/11600/6292
dc.description.abstract BACKGROUND: Sickle cell disease is the most common monogenic hereditary disease in Brazil. Although strokes are one of the main causes of morbidity and mortality in these patients, the use of transcranial Doppler to identify children at risk is not universally used. OBJECTIVE: To develop Brazilian guidelines for the use of transcranial Doppler in sickle cell disease children and adolescents, so that related health policies can be expanded, and thus contribute to reduce morbidity and mortality. METHODS: The guidelines were formulated in a consensus meeting of experts in transcranial Doppler and sickle cell disease. The issues discussed were previously formulated and scientific articles in databases (MEDLINE, SciELO and Cochrane) were carefully analyzed. The consensus for each question was obtained by a vote of experts on the specific theme. RESULTS: Recommendations were made, including indications for the use of transcranial Doppler according to the sickle cell disease genotype and patients age; the necessary conditions to perform the exam and its periodicity depending on exam results; the criteria for the indication of blood transfusions and iron chelation therapy; the indication of hydroxyurea; and the therapeutic approach in cases of conditional transcranial Doppler. CONCLUSION: The Brazilian guidelines on the use of transcranial doppler in sickle cell disease patients may reduce the risk of strokes, and thus reduce the morbidity and mortality and improve the quality of life of sickle cell disease patients. en
dc.format.extent 43-48
dc.language.iso eng
dc.publisher Associação Brasileira de Hematologia e Hemoterapia e Terapia Celular
dc.relation.ispartof Revista Brasileira de Hematologia e Hemoterapia
dc.rights Acesso aberto
dc.subject Ultrasonography, doppler, transcranial en
dc.subject Anemia, sickle cell en
dc.subject Hemoglobin en
dc.subject Stroke en
dc.subject Child en
dc.subject Adolescent en
dc.subject Guideline en
dc.title Brazilian Guidelines for transcranial doppler in children and adolescents with sickle cell disease en
dc.type Artigo
dc.contributor.institution Instituto Estadual de Hematologia Arthur de Siqueira Cavalcanti
dc.contributor.institution Faculdade de Ciências Médicas da Santa Casa de São Paulo
dc.contributor.institution Fundação de Hematologia e Hemoterapia de Pernambuco
dc.contributor.institution Universidade de São Paulo (USP)
dc.contributor.institution Fundação Hemocentro
dc.contributor.institution Fundação Centro de Hematologia e Hemoterapia de Minas Gerais
dc.contributor.institution UFRGS Hospital de Clínicas de Porto Alegre Serviço de Hematologia e Transplante de Medula Óssea
dc.contributor.institution Universidade Federal de São Paulo (UNIFESP)
dc.contributor.institution Universidade Federal do Paraná Hospital de Clínicas Serviço de Neurologia
dc.contributor.institution Ecodopler Laboratório
dc.contributor.institution Universidade Federal do Rio de Janeiro Instituto de Puericultura e Pediatria Martagão Gesteira
dc.contributor.institution Medical University of South Carolina
dc.description.affiliation Instituto Estadual de Hematologia Arthur de Siqueira Cavalcanti
dc.description.affiliation Faculdade de Ciências Médicas da Santa Casa de São Paulo
dc.description.affiliation Fundação de Hematologia e Hemoterapia de Pernambuco
dc.description.affiliation Universidade de São Paulo Faculdade de Medicina de Ribeirão Preto Hospital das Clínicas
dc.description.affiliation Fundação Hemocentro
dc.description.affiliation Fundação Centro de Hematologia e Hemoterapia de Minas Gerais
dc.description.affiliation UFRGS Hospital de Clínicas de Porto Alegre Serviço de Hematologia e Transplante de Medula Óssea
dc.description.affiliation Universidade Federal de São Paulo (UNIFESP)
dc.description.affiliation Universidade Federal do Paraná Hospital de Clínicas Serviço de Neurologia
dc.description.affiliation Ecodopler Laboratório
dc.description.affiliation Universidade Federal do Rio de Janeiro Instituto de Puericultura e Pediatria Martagão Gesteira
dc.description.affiliation Medical University of South Carolina
dc.description.affiliation Universidade de São Paulo Faculdade de Medicina
dc.description.affiliationUnifesp UNIFESP
dc.identifier.file S1516-84842011000100014.pdf
dc.identifier.scielo S1516-84842011000100014
dc.identifier.doi 10.5581/1516-8484.20110014
dc.description.source SciELO



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