Anaphylaxis in Latin America: a report of the online Latin American survey on anaphylaxis (OLASA)

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dc.contributor.author Solé, Dirceu [UNIFESP]
dc.contributor.author Ivancevich, Juan Carlos
dc.contributor.author Borges, Mario Sanchez
dc.contributor.author Coelho, Magna Adaci
dc.contributor.author Rosario Filho, Nelson Augusto
dc.contributor.author Ardusso, Ledit Ramón Francisco
dc.contributor.author Bernd, Luis Antônio Guerra
dc.date.accessioned 2015-06-14T13:42:51Z
dc.date.available 2015-06-14T13:42:51Z
dc.date.issued 2011-01-01
dc.identifier http://dx.doi.org/10.1590/S1807-59322011000600004
dc.identifier.citation Clinics. Faculdade de Medicina / USP, v. 66, n. 6, p. 943-947, 2011.
dc.identifier.issn 1807-5932
dc.identifier.uri http://repositorio.unifesp.br/handle/11600/6244
dc.description.abstract OBJECTIVES: The aims of the Online Latin American Survey of Anaphylaxis (OLASA) were to identify the main clinical manifestations, triggers, and treatments of severe allergic reactions in patients who were seen by allergists from July 2008 to June 2010 in 15 Latin American countries and Portugal (n =634). RESULTS: Of all patients, 68.5% were older than 18 years, 41.6% were male, and 65.4% experienced the allergic reaction at home. The etiologic agent was identified in 87.4% of cases and predominantly consisted of drugs (31.2%), foods (23.3%), and insect stings (14.9%). The main symptom categories observed during the acute episodes were cutaneous (94.0%) and respiratory (79.0%). The majority of patients (71.6%) were treated initially by a physician (office/emergency room) within the first hour after the reaction occurred (60.2%), and 43.5% recovered in the first hour after treatment. Most patients were treated in an emergency setting, but only 37.3% received parenteral epinephrine alone or associated with other medication. However, 80.5% and 70.2% were treated with corticosteroids or antihistamines (alone or in association), respectively. A total of 12.9% of the patients underwent reanimation maneuvers, and 15.2% were hospitalized. Only 5.8% of the patients returned to the emergency room after discharge, with 21.7% returning in the first 6 hours after initial treatment. CONCLUSION: The main clinical manifestations of severe allergic reactions were cutaneous. The etiologic agents that were identified as causing these acute episodes differed according to age group. Following in order: drugs (31.2%), foods (23.3% and insect stings (14.9%) in adults with foods predominance in children. Treatment provided for acute anaphylactic reactions was not appropriate. It is necessary to improve educational programs in order to enhance the knowledge on this potentially fatal emergency. en
dc.format.extent 943-947
dc.language.iso eng
dc.publisher Faculdade de Medicina / USP
dc.relation.ispartof Clinics
dc.rights Acesso aberto
dc.subject Anaphylaxis en
dc.subject Drugs en
dc.subject Food en
dc.subject Hymenoptera sp en
dc.subject Epinephrine en
dc.title Anaphylaxis in Latin America: a report of the online Latin American survey on anaphylaxis (OLASA) en
dc.type Artigo
dc.contributor.institution Universidade Federal de São Paulo (UNIFESP)
dc.contributor.institution Universidad del Salvador Medical School Immunology
dc.contributor.institution Clínica Santa Isabel Head of the Division of Allergy and Immunology
dc.contributor.institution Centro Médico-Docente La Trinidad Allergy and Clinical Immunology Department
dc.contributor.institution Clínica El Avila Head of Allergy and Immunology Department
dc.contributor.institution University of Montes Claros
dc.contributor.institution Federal University of Paraná Department of Pediatrics
dc.contributor.institution National University of Rosario Faculty of Medical Sciences
dc.contributor.institution Federal Faculty Foundation of Medical Sciences of Porto Alegre Division of Immunology and Immunopathology
dc.description.affiliation Federal University of São Paulo Clinical Immunology and Rheumatology Department of Pediatrics Division of Allergy
dc.description.affiliation Universidad del Salvador Medical School Immunology
dc.description.affiliation Clínica Santa Isabel Head of the Division of Allergy and Immunology
dc.description.affiliation Centro Médico-Docente La Trinidad Allergy and Clinical Immunology Department
dc.description.affiliation Clínica El Avila Head of Allergy and Immunology Department
dc.description.affiliation University of Montes Claros
dc.description.affiliation Federal University of Paraná Department of Pediatrics
dc.description.affiliation National University of Rosario Faculty of Medical Sciences
dc.description.affiliation Federal Faculty Foundation of Medical Sciences of Porto Alegre Division of Immunology and Immunopathology
dc.description.affiliationUnifesp UNIFESP, Clinical Immunology and Rheumatology Department of Pediatrics Division of Allergy
dc.identifier.file S1807-59322011000600004.pdf
dc.identifier.scielo S1807-59322011000600004
dc.identifier.doi 10.1590/S1807-59322011000600004
dc.description.source SciELO
dc.identifier.wos WOS:000293410000004



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