Anaphylaxis in Latin America: a report of the online Latin American survey on anaphylaxis (OLASA)

Anaphylaxis in Latin America: a report of the online Latin American survey on anaphylaxis (OLASA)

Autor Solé, Dirceu Autor UNIFESP Google Scholar
Ivancevich, Juan Carlos Google Scholar
Borges, Mario Sanchez Google Scholar
Coelho, Magna Adaci Google Scholar
Rosario Filho, Nelson Augusto Google Scholar
Ardusso, Ledit Ramón Francisco Google Scholar
Bernd, Luis Antônio Guerra Google Scholar
Instituição Universidade Federal de São Paulo (UNIFESP)
Universidad del Salvador Medical School Immunology
Clínica Santa Isabel Head of the Division of Allergy and Immunology
Centro Médico-Docente La Trinidad Allergy and Clinical Immunology Department
Clínica El Avila Head of Allergy and Immunology Department
University of Montes Claros
Federal University of Paraná Department of Pediatrics
National University of Rosario Faculty of Medical Sciences
Federal Faculty Foundation of Medical Sciences of Porto Alegre Division of Immunology and Immunopathology
Resumo OBJECTIVES: The aims of the Online Latin American Survey of Anaphylaxis (OLASA) were to identify the main clinical manifestations, triggers, and treatments of severe allergic reactions in patients who were seen by allergists from July 2008 to June 2010 in 15 Latin American countries and Portugal (n =634). RESULTS: Of all patients, 68.5% were older than 18 years, 41.6% were male, and 65.4% experienced the allergic reaction at home. The etiologic agent was identified in 87.4% of cases and predominantly consisted of drugs (31.2%), foods (23.3%), and insect stings (14.9%). The main symptom categories observed during the acute episodes were cutaneous (94.0%) and respiratory (79.0%). The majority of patients (71.6%) were treated initially by a physician (office/emergency room) within the first hour after the reaction occurred (60.2%), and 43.5% recovered in the first hour after treatment. Most patients were treated in an emergency setting, but only 37.3% received parenteral epinephrine alone or associated with other medication. However, 80.5% and 70.2% were treated with corticosteroids or antihistamines (alone or in association), respectively. A total of 12.9% of the patients underwent reanimation maneuvers, and 15.2% were hospitalized. Only 5.8% of the patients returned to the emergency room after discharge, with 21.7% returning in the first 6 hours after initial treatment. CONCLUSION: The main clinical manifestations of severe allergic reactions were cutaneous. The etiologic agents that were identified as causing these acute episodes differed according to age group. Following in order: drugs (31.2%), foods (23.3% and insect stings (14.9%) in adults with foods predominance in children. Treatment provided for acute anaphylactic reactions was not appropriate. It is necessary to improve educational programs in order to enhance the knowledge on this potentially fatal emergency.
Palavra-chave Anaphylaxis
Drugs
Food
Hymenoptera sp
Epinephrine
Idioma Inglês
Data de publicação 2011-01-01
Publicado em Clinics. Faculdade de Medicina / USP, v. 66, n. 6, p. 943-947, 2011.
ISSN 1807-5932 (Sherpa/Romeo, fator de impacto)
Publicador Faculdade de Medicina / USP
Extensão 943-947
Fonte http://dx.doi.org/10.1590/S1807-59322011000600004
Direito de acesso Acesso aberto Open Access
Tipo Artigo
Web of Science WOS:000293410000004
SciELO S1807-59322011000600004 (estatísticas na SciELO)
Endereço permanente http://repositorio.unifesp.br/handle/11600/6244

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