Restless legs syndrome in subjects with a knee prosthesis: evidence that symptoms are generated in the periphery

Restless legs syndrome in subjects with a knee prosthesis: evidence that symptoms are generated in the periphery

Autor Pereira Júnior, José Carlos Google Scholar
Silva Neto, João Luiz Pereira da Google Scholar
Pradella-Hallinan, Márcia Lurdes de Cássia Autor UNIFESP Google Scholar
Instituição Faculdade de Medicina de Jundiaí
Universidade Federal de São Paulo (UNIFESP)
Resumo OBJECTIVE: There are no data adressing the prevalence of restless legs syndrome in subjects who have knee prosthesis. Therefore, we conducted a cross-sectional survey of subjects who underwent knee prosthesis surgery. METHOD: A total of 107 subjects (30 male, 77 female) were interviewed over the telephone regarding restless legs syndrome symptoms. If the patients exhibited symptoms of the syndrome, we conducted face-to-face interviews. Lastly, a therapeutic test with pramipexole was proposed for each subject. RESULTS: In our cohort, 7 males (23%) and 30 females (39%) had restless legs syndrome. Of these, 6 males and 23 females were submitted to face-to-face-interview. Of the males, 5 (83%) had restless legs after the knee surgeryexclusively in the operated leg- and reported no family restless legs history. One man had a prior case of bilateral restless legs syndrome, a positive family history and claimed exacerbation of symptoms in the operated leg. Among the females, 16 (69%) had restless legs prior to surgery. A total of 10 female patients reported bilateral symptoms, with fewer symptoms in the operated leg, while 6 displayed a worse outcome in the operated leg. The 7 females (31%) without restless legs prior to surgery and without a family history experienced symptoms only in the operated leg. All subjects responded favorably to the pramipexole therapeutic test. CONCLUSION: Our results suggest that secondary unilateral restless legs syndrome may ensue from knee prosthesis surgery and that the symptoms are generated in the peripheral nervous system.
Palavra-chave Restless Legs Syndrome
RLS pathophysiology
Knee prosthesis
Idioma Inglês
Data de publicação 2011-01-01
Publicado em Clinics. Faculdade de Medicina / USP, v. 66, n. 11, p. 1955-1959, 2011.
ISSN 1807-5932 (Sherpa/Romeo, fator de impacto)
Publicador Faculdade de Medicina / USP
Extensão 1955-1959
Fonte http://dx.doi.org/10.1590/S1807-59322011001100017
Direito de acesso Acesso aberto Open Access
Tipo Artigo
Web of Science WOS:000297498600017
SciELO S1807-59322011001100017 (estatísticas na SciELO)
Endereço permanente http://repositorio.unifesp.br/handle/11600/6220

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