High-energy extracorporeal shockwave therapy in a patellar tendon animal model: a vascularizationfocused study

High-energy extracorporeal shockwave therapy in a patellar tendon animal model: a vascularizationfocused study

Author Penteado, Fernando Travaglini Autor UNIFESP Google Scholar
Faloppa, Flávio Autor UNIFESP Google Scholar
Giusti, Guilherme Autor UNIFESP Google Scholar
Moraes, Vinícius Ynoe de Autor UNIFESP Google Scholar
Belloti, Joao Carlos Autor UNIFESP Google Scholar
Santos, João Baptista Gomes dos Autor UNIFESP Google Scholar
Institution Universidade Federal de São Paulo (UNIFESP)
Abstract OBJECTIVE: The aim of this study was to analyze the effect of high-energy extracorporeal shockwave therapy on tendon angiogenesis in the patellar tendons of rabbits. We sought to investigate whether different voltage and number pulses modify the angiogenesis pattern. INTRODUCTION: High-energy extracorporeal shockwave therapy is an option in the treatment of orthopedic diseases such as chronic tendonitis. Despite its potential clinical applicability, there have been few studies on this technique that examine both its clinical effectiveness and its effect on angiogenesis. METHODS: High-energy extracorporeal shockwave therapy was applied at the tibial insertion of the left patellar ligament in 30 rabbits that were separated into six groups that differed in terms of the voltage and number of pulses that were applied by high-energy extracorporeal shockwave therapy. The tibial insertion in the right legs of the animals was used as the control. After six weeks, we performed histological analysis on the region and quantified the number of blood vessels. RESULTS: No significant differences in the number of blood vessels between the left and right patellar tendons were found within groups. Additionally, no significant differences in the number of blood vessels in the left patellar tendons were found between groups. CONCLUSIONS: The application of high-energy extracorporeal shockwave therapy did not cause a change in vascularization in the patellar tendon in rabbits.
Keywords High-energy shock waves
Patellar ligament
Neovascularization
Animal model
Language English
Date 2011-01-01
Published in Clinics. Faculdade de Medicina / USP, v. 66, n. 9, p. 1611-1614, 2011.
ISSN 1807-5932 (Sherpa/Romeo, impact factor)
Publisher Faculdade de Medicina / USP
Extent 1611-1614
Origin http://dx.doi.org/10.1590/S1807-59322011000900018
Access rights Open access Open Access
Type Article
Web of Science ID WOS:000297498400018
SciELO ID S1807-59322011000900018 (statistics in SciELO)
URI http://repositorio.unifesp.br/handle/11600/6219

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