Granulocytic sarcoma presented as a reactivation of chronic myeloid leukemia after allogenic marrow transplantation

Granulocytic sarcoma presented as a reactivation of chronic myeloid leukemia after allogenic marrow transplantation

Author Oliveira, José Salvador Rodrigues de Autor UNIFESP Google Scholar
Chauffaille, Maria de Lourdes Lopes Ferrari Autor UNIFESP Google Scholar
Colleoni, Gisele Wally Braga Autor UNIFESP Google Scholar
Morelli, Vânia Maris Autor UNIFESP Google Scholar
Hauache, Omar Magid Autor UNIFESP Google Scholar
Alberti, Vânia Nosé Autor UNIFESP Google Scholar
Kerbauy, José Autor UNIFESP Google Scholar
Institution Universidade Federal de São Paulo (UNIFESP)
Abstract The authors report the case of a chronic myeloid leukemia (CML) patient submitted to allogenic bone marrow transplantation, who had probably never entered complete remission. The disease was reactivated as a granulocytic sarcoma, next to a platinum plate installed to correct a tibia fracture 11 years earlier. Its final event was a myeloid Ph1+ blastic crisis that was unsuccessfully treated with high doses of sc interferon and citarabine.

Os autores relatam um caso de leucemia mielóide crônica tratada com transplante alogênico de medula óssea e que provavelmente nunca entrou em remissão completa da doença. A paciente apresentou reativação como sarcoma granulocítico junto a uma placa de platina instalada há 11 anos, após fratura de tíbia. Descrevem também outras manifestações de recidiva e término em crise blástica mielóide Ph1+ sem sucesso tratada com altas doses de interferon se e citarabina.
Keywords Granulocytic sarcoma
Bone marrow transplantation
Chronic myeloid leukemia
Hypercalcemia
Language English
Date 1998-03-01
Published in São Paulo Medical Journal. Associação Paulista de Medicina - APM, v. 116, n. 2, p. 1689-1691, 1998.
ISSN 1516-3180 (Sherpa/Romeo)
Publisher Associação Paulista de Medicina - APM
Extent 1689-1691
Origin http://dx.doi.org/10.1590/S1516-31801998000200009
Access rights Open access Open Access
Type Article
SciELO ID S1516-31801998000200009 (statistics in SciELO)
URI http://repositorio.unifesp.br/handle/11600/599

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