Obsessive-compulsive symptoms are associated with psychiatric comorbidities, behavioral and clinical problems: a population-based study of Brazilian school children

Obsessive-compulsive symptoms are associated with psychiatric comorbidities, behavioral and clinical problems: a population-based study of Brazilian school children

Author Alvarenga, Pedro G. Google Scholar
Rosario, Maria C. do Autor UNIFESP Google Scholar
Cesar, Raony C. Google Scholar
Manfro, Gisele G. Google Scholar
Moriyama, Tais S. Google Scholar
Bloch, Michael H. Google Scholar
Shavitt, Roseli G. Google Scholar
Hoexter, Marcelo Q. Google Scholar
Coughlin, Catherine G. Google Scholar
Leckman, James F. Google Scholar
Miguel, Euripedes C. Google Scholar
Abstract Pediatric-onset obsessive-compulsive disorder (OCD) is underdiagnosed, and many affected children are untreated. The present study seeks to evaluate the presence and the clinical impact of OCD and obsessive-compulsive symptoms (OCS) in a large sample of school-age children. In Phase I, we performed an initial screening using the Family History Screen (FHS). In Phase II, we identified an "at-risk" sample, as well as a randomly selected group of children. A total of 2,512 children (6-12 years old) were assessed using the FHS, the Development and Well-Being Assessment (DAWBA), the Strengths and Difficulties Questionnaire (SDQ), and the Child Behavior Checklist (CBCL). Data analyses included descriptive and multivariate analytical techniques. 2,512 children (mean age: 8.86 +/- A 1.84 years; 55.0 % male) were categorized into one of the three diagnostic groups: OCD (n = 77), OCS (n = 488), and unaffected controls (n = 1,947). There were no significant socio-demographic differences (age, gender, socioeconomic status) across groups. The OCS group resembled the OCD on overall impairment, including school problems and delinquent behaviors. However, the OCD group did have significantly higher rates of several comorbid psychiatric disorders, including separation anxiety, generalized anxiety, and major depressive disorder, than OCS or unaffected controls. Moreover, the OCD group also scored higher than the SDQ, as well as on each of CBCL items rated by the parent. Our findings suggest that there is a psychopathological continuum between OCS and OCD in school-aged children. The presence of OCS is associated with functional impairment, which needs further investigation in longitudinal studies.
Keywords Child and adolescent psychiatry
Comorbidities
Epidemiology
Obsessive-compulsive disorder
School-aged children
xmlui.dri2xhtml.METS-1.0.item-coverage New York
Language English
Sponsor National Institutes of Health
Tourette Syndrome Association
Patterson Trust Foundation
Rembrandt Foundation
Grifols, LLC
Klingenstein Third Generation Foundation
Oxford University Press
Date 2016
Published in European Child & Adolescent Psychiatry. New York, v. 25, n. 2, p. 175-182, 2016.
ISSN 1018-8827 (Sherpa/Romeo, impact factor)
Publisher Springer
Extent 175-182
Origin https://doi.org/10.1007/s00787-015-0723-3
Access rights Open access Open Access
Type Article
Web of Science ID WOS:000369325900006
URI https://repositorio.unifesp.br/handle/11600/58488

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