Associations Between Dietary Intake Before 6 Months of Age and Rapid Weight Gain Among HIV-exposed Uninfected Infants

Associations Between Dietary Intake Before 6 Months of Age and Rapid Weight Gain Among HIV-exposed Uninfected Infants

Author Neri, Daniela Autor UNIFESP Google Scholar
Oliveira, Fernanda L. C. Autor UNIFESP Google Scholar
Carvalho, Aline M. Google Scholar
Somarriba, Gabriel A. Google Scholar
Scott, Gwendolyn B. Google Scholar
Miller, Tracie L. Google Scholar
Abstract Introduction: HIV-exposed, uninfected (HEU) infants are potentially at risk for cardiovascular disease due to in utero exposures. Feeding practices of the infant could compound this risk. Few studies have, however, evaluated dietary intake of HEU infants. We determined dietary factors associated with rapid weight gain (RWG) among HEU infants from birth to 6 months followed at the University of Miami HIV Screening Program. Methods: In this cross-sectional analysis, logistic regression was used to determine dietary factors associated with RWG defined as a >0.67 SD change in weight-for-age z score from birth to assessment (0.3-6 months). Other covariates included demographics, birth, maternal and gestational characteristics, and antiretroviral exposures. Results: A total of 86 full-term HEU infants with a mean age of 3.4 months (SD 1.8 months) were included in this analysis. Fifty-five percent of mothers were obese. Overall, 39.5% of infants exhibited RWG. A significant association between consumption of infant cereal and RWG (odds ratio, 3.52; 95% confidence interval, 1.02-12.10) was found after adjusting for birth weight, current age, and energy intake. Those infants who consumed the highest tertile of protein were less likely to gain weight rapidly after adjusting for the same covariates (odds ratio, 0.15; 95% confidence interval, 0.02-0.94). Conclusions: Overall differences in weight gain during early infancy are at least partly explained by means of infant feeding in young HEU infants in the United States. Dietary counseling for families of HEU should reinforce current feeding practice recommendations of the American Academy of Pediatrics.
Keywords early complementary feeding
HIV-exposed
uninfected infants
obesogenic feeding practice
rapid weight gain
xmlui.dri2xhtml.METS-1.0.item-coverage Philadelphia
Language English
Sponsor National Institutes of Health (National Heart, Lung, and Blood Institute)
National Institutes of Health (Eunice Kennedy Shriver National Institute of Child Health and Human Development)
Micah Batchelor Award for Research Excellence
Coulter Jones Foundation
Department of Health and Human Services Health Resources and Services Administration
CAPES Foundation, Ministry of Education of Brazil (Brasilia, Brazil)
Grant number National Institutes of Health (National Heart, Lung, and Blood Institute): 1 R01 HL095127
National Institutes of Health (Eunice Kennedy Shriver National Institute of Child Health and Human Development): 1 R01 HD060325
Department of Health and Human Services Health Resources and Services Administration: H 12HA 00028
Date 2017
Published in Journal Of Pediatric Gastroenterology And Nutrition. Philadelphia, v. 65, n. 5, p. E104-E109, 2017.
ISSN 0277-2116 (Sherpa/Romeo, impact factor)
Publisher Lippincott Williams & Wilkins
Extent E104-E109
Origin http://dx.doi.org/10.1097/MPG.0000000000001607
Access rights Open access Open Access
Type Article
Web of Science ID WOS:000417650600003
URI https://repositorio.unifesp.br/handle/11600/58225

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