Occurrence of pharmaceuticals and cocaine in a Brazilian coastal zone

Occurrence of pharmaceuticals and cocaine in a Brazilian coastal zone

Author Seabra Pereira, Camilo D. Google Scholar
Maranho, Luciane A. Google Scholar
Cortez, Fernando S. Google Scholar
Pusceddu, Fabio H. Google Scholar
Santos, Aldo R. Google Scholar
Ribeiro, Daniel A. Autor UNIFESP Google Scholar
Cesar, Augusto Google Scholar
Guimaraes, Luciana L. Google Scholar
Abstract The present study determined environmental concentrations of pharmaceuticals, cocaine, and the main human metabolite of cocaine in seawater sampled from a subtropical coastal zone (Santos, Brazil). The Santos Bay is located in a metropolitan region and receives over 7367 m(3) of wastewater per day. Five sample points under strong influence of the submarine sewage outfall were chosen. Through quantitative analysis by LC-MS/MS, 33 compounds were investigated. Seven pharmaceuticals (atenolol, acetaminophen, caffeine, losartan, valsartan, diclofenac, and ibuprofen), an illicit drug (cocaine), and its main humanmetabolite (benzoylecgonine) were detected at least once in seawater sampled from Santos Bay at concentrations that ranged from ng.L-1 to mu g.L-1. In light of the possibility of bioaccumulation and harmful effects, the high concentrations of pharmaceuticals and cocaine found in this marine subtropical ecosystem are of environmental concern. (C) 2016 Elsevier B.V. All rights reserved.
Keywords Pharmaceuticals
Cocaine
Submarine sewage outfall
Subtropical zone
Marine environment
xmlui.dri2xhtml.METS-1.0.item-coverage Amsterdam
Language English
Sponsor Conselho Nacional de Desenvolvimento Cientifico e Tecnologico (CNPq)
Grant number CNPq: 481358/2012-9
CNPq: 481553/2012-6
Date 2016
Published in Science Of The Total Environment. Amsterdam, v. 548, p. 148-154, 2016.
ISSN 0048-9697 (Sherpa/Romeo, impact factor)
Publisher Elsevier Science Bv
Extent 148-154
Origin http://dx.doi.org/10.1016/j.scitotenv.2016.01.051
Access rights Closed access
Type Article
Web of Science ID WOS:000370246000017
URI https://repositorio.unifesp.br/handle/11600/57764

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