The suicidality continuum in a large sample of obsessive-compulsive disorder (OCD) patients

The suicidality continuum in a large sample of obsessive-compulsive disorder (OCD) patients

Author Velloso, Patricia Autor UNIFESP Google Scholar
Piccinato, Carlos Autor UNIFESP Google Scholar
Ferrao, Y. Google Scholar
Perin, Eduardo Aliende Autor UNIFESP Google Scholar
Cesar, R. Google Scholar
Fontenelle, L. Google Scholar
Hounie, Ana Gabriela Autor UNIFESP Google Scholar
Rosario, Maria Conceicao do Autor UNIFESP Google Scholar
Abstract Background: Obsessive-compulsive disorder (OCD) has a chronic course leading to huge impact in the patient's functioning. Suicidal thoughts and attempts are much more frequent in OCD subjects than once thought before. Aim: To empirically investigate whether the suicidal phenomena could be analyzed as a suicidality severity continuum and its association with obsessive-compulsive (OC) symptom dimensions and quality of life (QoL), in a large OCD sample. Methods: Cross-sectional study with 548 patients diagnosed with OCD according to the DSM-IV criteria, interviewed in the Brazilian OCD Consortium (C-TOC) sites. Patients were evaluated by OCD experts using standardized instruments including: Yale-Brown Obsessive-Compulsive Scale (YBOCS)

Dimensional Yale-Brown Obsessive-Compulsive Scale (DYBOCS)

Beck Depression and Anxiety Inventories

Structured Clinical Interview for DSM-IV (SCID)

and the SF-36 QoL Health Survey. Results: There were extremely high correlations between all the suicidal phenomena. OCD patients with suicidality had significantly lower QoL, higher severity in the "sexual/religious'', "aggression'' and "symmetry/ordering'' OC symptom dimensions, higher BDI and BA scores and a higher frequency of suicide attempts in a family member. In the regression analysis, the factors that most impacted suicidality were the sexual dimension severity, the SF-36 QoL Mental Health domain, the severity of depressive symptoms and a relative with an attempted suicide history. Conclusions: Suicidality could be analyzed as a severity continuum and patients should be carefully monitored since they present with suicidal ideation. Lower QoL scores, higher scores on the sexual dimension and a family history of suicide attempts should be considered as risk factors for suicidality among OCD patients. (C) 2016 Elsevier Masson SAS. All rights reserved.
Keywords Suicidality
Quality of life
OCD
xmlui.dri2xhtml.METS-1.0.item-coverage Paris
Language English
Date 2016
Published in European Psychiatry. Paris, v. 38, p. 1-7, 2016.
ISSN 0924-9338 (Sherpa/Romeo, impact factor)
Publisher Elsevier France-Editions Scientifiques Medicales Elsevier
Extent 1-7
Origin http://dx.doi.org/10.1016/j.eurpsy.2016.05.003
Access rights Closed access
Type Article
Web of Science ID WOS:000386336900001
URI https://repositorio.unifesp.br/handle/11600/56984

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