Evaluation of europium-doped HA/beta-TCP ratio fluorescence in biphasic calcium phosphate nanocomposites controlled by the pH value during the synthesis

Evaluation of europium-doped HA/beta-TCP ratio fluorescence in biphasic calcium phosphate nanocomposites controlled by the pH value during the synthesis

Author Silva, Flavia R. O. Google Scholar
Lima, Nelson B. Google Scholar
Guilhen, Sabine N. Google Scholar
Courrol, Lilia Coronato Autor UNIFESP Google Scholar
Bressiani, Ana Helena A. Google Scholar
Abstract Europium-doped hydroxyapatite (HA), beta-tricalcium phosphate (beta-TCP) and biphasic phosphate nanopowders were synthesized by co-precipitation method and their crystal structures and fluorescence properties were investigated depending on the pH of the starting solution. In the range of pH 6-10, HA and beta-TCP phases coexist The beta-TCP proportion increased as the pH of the solution decreased, while HA yields decreased. At pH below 6, monophasic beta-TCP powder was obtained after thermal treatment. In particular, HA and beta-TCP can be used as luminescent materials when activated by Eu3+ ions in substitution of Ca2+ ions. Herein, the Eu3+ ions doped HA and beta-TCP phase composition were analyzed in order to investigate the fluorescence emission of the HA, beta-TCP and biphasic compounds. Eu-doped HA exhibited a red-orange emission at 575 nm with several minor peaks at 610-640 nm, while Eu-doped beta-TCP had an unexpected strong red emission at 610-620 nm and a secondary band at 590-600 nm. In fact, the Eu:beta-TCP integrated emission area is almost 20-fold higher than Eu:HA for the same europium ion concentration. These results demonstrate the potential of Eu:beta-TCP as biomarker for medical applications, as drug release and targeting based on their luminescent properties. (C) 2016 Elsevier B.V. All rights reserved.
Keywords Hydroxyapatite
Beta tricalcium phosphate
Biphasic phosphate
Europium
Fluorescence
pH synthesis
xmlui.dri2xhtml.METS-1.0.item-coverage Amsterdam
Language English
Sponsor Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
Grant number CNPq: 480892/2013-0
Date 2016
Published in Journal Of Luminescence. Amsterdam, v. 180, p. 177-182, 2016.
ISSN 0022-2313 (Sherpa/Romeo, impact factor)
Publisher Elsevier Science Bv
Extent 177-182
Origin http://dx.doi.org/10.1016/j.jlumin.2016.08.030
Access rights Closed access
Type Article
Web of Science ID WOS:000386314300027
URI https://repositorio.unifesp.br/handle/11600/56691

Show full item record




File

File Size Format View

There are no files associated with this item.

This item appears in the following Collection(s)

Search


Browse

Statistics

My Account