An evaluation of new circle system of anesthesia. Quantitative anesthesia with isoflurane in new zealand rabbits

An evaluation of new circle system of anesthesia. Quantitative anesthesia with isoflurane in new zealand rabbits

Alternative title Avaliação de um novo sistema circular de anestesia: anestesia quantitativa com isuflorane em coelhos
Author Fonseca, Neuber M. Google Scholar
Goldenberg, Saul Autor UNIFESP Google Scholar
Eurides, Duvaldo Google Scholar
Novo, Neil Ferreira Autor UNIFESP Google Scholar
Lima, Cirilo A. P. Google Scholar
Institution Federal University of Uberlândia Department of Surgery and Anesthesiology
Universidade Federal de São Paulo (UNIFESP)
Federal University of Uberlândia Department of Animal Medicine
Catholic University of SP Faculty of Medicine of Sorocaba
Abstract A small circuit system of anesthesia was developed by Fonseca and Goldenberg in 1993. The authors used in this study New Zealand White (NZW) rabbits under closed system anesthetic regiment by insoflurane. Twenty male adult New Zealand rabbits were distributed in two groups of ten animals. No premedicant drugs were given. Endotraqueal intubation was made after intravenous administration of propofol (10mg/kg). Insoflurane was used to anesthesia management, administred by lowflow closed system technique with cooper kettle vaporizer, fixed by pre-calculated vaporizing flow in double times intervals. The group II underwent surgical periostal scratching in the medial tibial surface at the proximal shaft. Rabbits breathed spontaneously. Hypotensio, hypercapnia and respiratory acidosis were characteristic of the cardiopulmonary effects of the anesthesia. The corneal reflex and pinch reflex was useful as reliable indicators of anesthesic depth. Manual or mechanical ventilation should be considered as a way of improving alveolar ventilation and normalize blood-gas values. The system developed by Fonseca and Goldenberg was considered suitable for anesthesic management in rabbits.

Um sistema circular de anestesia para animais de pequeno porte foi desenvolvido por FONSECA e GOLDENBERG, em 1993. No presente estudo foram utilizados 20 coelhos brancos linhagem Nova Zelândia, submetidos ao sistema com isoflurane, distribuidos em dois grupos de 10 animais. O grupo I, controle, que foi apenas anestesiado e o grupo II foi submetido a raspagem periostal da parte proximal e medial da tíbia. Não foi administrada droga pré-anestésica. Após administração do propofol intravenoso (10mg/kg) procedeu-se a intubação endotraqueal. O isuflorane foi administrado lentamente no sistema circular de anestesia. Os animais respiravam espontaneamente. Houve efeitos cardiorespiratórios conseqüentes da anestesia, tais como, hipotensão, hipercapnia e acidose respiratória. O controle do plano anestésico foi realizado mediante os reflexos corneano e pelo pinçamento. O sistema desenvolvido por FONSECA e GOLDENBERG foi considerado satisfatório para anestesia em coelhos.
Keywords Anesthesia
Rabbits
Anestesia
Coelhos
Language English
Date 1997-12-01
Published in Acta Cirurgica Brasileira. Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia, v. 12, n. 4, p. 246-248, 1997.
ISSN 0102-8650 (Sherpa/Romeo)
Publisher Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia
Extent 246-248
Origin http://dx.doi.org/10.1590/S0102-86501997000400006
Access rights Open access Open Access
Type Article
SciELO ID S0102-86501997000400006 (statistics in SciELO)
URI http://repositorio.unifesp.br/handle/11600/549

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