Body Mass Index and skin reactivity to histamine and Dermatophagoides pteronyssinus in children and adolescents followed in a pediatric allergy service

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dc.contributor.author Franco, A. Keller [UNIFESP]
dc.contributor.author Sarni, R. Oselka [UNIFESP]
dc.contributor.author Mallozi, M. Carvalho [UNIFESP]
dc.contributor.author Sole, D. [UNIFESP]
dc.date.accessioned 2020-07-13T11:53:17Z
dc.date.available 2020-07-13T11:53:17Z
dc.date.issued 2017
dc.identifier http://www.eurannallergyimm.com/cont/journals-articles/483/volume-body-mass-index-skin-reactivity.asp
dc.identifier.citation European Annals Of Allergy And Clinical Immunology. Fidenza, v. 49, n. 3, p. 110-113, 2017.
dc.identifier.issn 1764-1489
dc.identifier.uri https://repositorio.unifesp.br/handle/11600/54510
dc.description.abstract Rationale. Recent data suggest that the nutritional status assessed by body mass index (BMI) is positively associated with skin reactivity to histamine in children. Objective. To study the relation between BMI and skin reactivity to histamine and Dermatophagoides pteronyssinus in allergic children and adolescents. Methods. The medical charts of patients attended in our outpatient clinic between 2013 and 2014 (n = 972) were evaluated. Only patients with asthma, allergic rhinitis or wheezing infants sensitized to at least one aeroallergen were selected: a total of 626 patients (6 months to 19 year-olds en
dc.description.abstract 60.1% male) were enrolled. Weight (kg), height (m), BMI (weight/height(2)), and the mean diameter of the wheals induced by histamine (10 mg/ml) and Dermatophagoides pteronyssinus in skin prick tests (SPT) were obtained. Skin index (SI en
dc.description.abstract ratio of allergen-induced wheal diameter and corresponding histamine diameter) was also analyzed. Results. All patients had shown a mean wheal diameter of histamine greater than 1 mm. There was no increased skin reactivity to histamine with increasing BMI Z score (ZBMI). However, a significant correlation between BMI and the mean wheal of histamine was observed in patients < -1 ZBMI. Similar results were observed with Dermatophagoides pteronyssinus, (even considering the SI). Conclusions. We did not document interference of nutritional status (ZBMI) on the skin reactivity to histamine or Dermatophagoiodes pteronyssinus in atopic patients. Further investigation is required. en
dc.format.extent 110-113
dc.language.iso eng
dc.publisher Mattioli 1885
dc.relation.ispartof European Annals Of Allergy And Clinical Immunology
dc.rights Acesso aberto
dc.subject Allergic sensitization en
dc.subject histamine en
dc.subject skin index en
dc.subject skin prick tests en
dc.subject body mass index en
dc.title Body Mass Index and skin reactivity to histamine and Dermatophagoides pteronyssinus in children and adolescents followed in a pediatric allergy service en
dc.type Artigo
dc.description.affiliation Univ Fed Sao Paulo, Escola Paulista Med, Dept Pediat, Div Allergy Clin Immunol & Rheumatol, Sao Paulo, SP, Brazil
dc.description.affiliation Fac Med ABC, Dept Pediat, Sao Paulo, Brazil
dc.description.affiliationUnifesp Univ Fed Sao Paulo, Escola Paulista Med, Dept Pediat, Div Allergy Clin Immunol & Rheumatol, Sao Paulo, SP, Brazil
dc.description.source Web of Science
dc.identifier.wos WOS:000407852600003
dc.coverage Fidenza
dc.citation.volume 49
dc.citation.issue 3



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